Impact of disease activity statuses on mortality, new damage and severe new damage. Univariable and multivariable analyses
| Mortality | New damage** | Severe new damage*** | ||||
|---|---|---|---|---|---|---|
| Group | Unadjusted Hazard Ratio(95% CI) | Adjusted* Hazard Ratio(95% CI) | Unadjusted Hazard Ratio(95% CI) | Adjusted*Hazard Ratio(95% CI) | Unadjusted Hazard Ratio(95% CI) | Adjusted* Hazard Ratio(95% CI) |
| Remission (On/Off Therapy) | 0.46 (0.17–1.27) | 0.56 (0.20–1.55) | 0.47 (0.34–0.65) | 0.52 (0.37–0.72) | 0.30 (0.16–0.60) | 0.32 (0.15–0.65) |
| p-value | 0.1330 | 0.2623 | < 0.0001 | < 0.0001 | 0.0006 | 0.0017 |
| LLDAS | 0.65 (0.26–1.60) | 0.81 (0.32–2.02) | 0.69 (0.50–0.93) | 0.74 (0.54–1.01) | 0.41 (0.21–0.81) | 0.46 (0.23–0.91) |
| p-value | 0.3454 | 0.6476 | 0.0164 | 0.0610 | 0.0100 | 0.0247 |
| Non-Optimally Controlled | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
LLDAS: Lupus low disease activity status. *Adjusted by age at baseline, gender, ethnicity, socioeconomic status, years of instruction, medical coverage and first SDI. **One-point increment in the SDI. ***Three-point increment in the SDI.