CR1 polymorphisms distribution in patients with SLE with nephritis (LN+) and patients with SLE without nephritis (LN−)
| CR1 polymorphisms | Genotype or allele | LN− (n=135) | LN+ (n=162) | p Value | OR (95% CI) |
|---|---|---|---|---|---|
| CR1 intron 27 (A>T) | Genotype | ||||
| AA | 24 (18) | 36 (22) | 1 | Ref | |
| AT | 70 (52) | 80 (49) | 0.44 | 0.76 (0.41 to 1.40) | |
| TT | 41 (30) | 46 (29) | 0.40 | 0.74 (0.38 to 1.45) | |
| Allele | |||||
| A | 118 (43) | 152 (47) | 1 | Ref | |
| T | 152 (57) | 172 (53) | 0.45 | 0.87 (0.63 to 1.21) | |
| CR1 exon 22 (A>G) | Genotype | ||||
| AA | 8 (6) | 6 (4) | 1 | Ref | |
| AG | 55 (41) | 59 (36) | 0.58 | 1.43 (0.46 to 4.38) | |
| GG | 72 (53) | 97 (60) | 0.40 | 1.79 (0.59 to 5.40) | |
| Allele | |||||
| A | 71 (26) | 71 (22) | 1 | Ref | |
| G | 199 (74) | 253 (78) | 0.24 | 1.27 (0.87 to 1.85) | |
| CR1 exon 33 | Genotype | ||||
| (G>C) | CC | 14 (10) | 6 (4) | 1 | Ref |
| CG | 47 (35) | 57 (35) | 0.05 | 2.83 (1.00 to 7.93) | |
| GG | 74 (55) | 99 (61) | 0.03 | 3.12 (1.14 to 8.51) | |
| Allele | |||||
| C | 75 (28) | 69 (21) | 1 | Ref | |
| G | 195 (72) | 255 (79) | 0.06 | 1.42 (0.97 to 2.07) |
Note: Data are no. (%) of participants unless otherwise specified.
p Values were calculated by Fisher's exact test.
SLE, systemic lupus erythematosus.