Table 2

Sample baseline characteristics, total and by frailty classification

 Frailty classification
Total (n=152)Robust (n=44)Prefrail (n=77)Frail (n=31)p Value*
Sociodemographic
 Age, years48.0±12.348.0±14.246.7±11.851.0±10.00.25
 White64.5 (98)63.6 (28)68.8 (53)54.8 (17)0.39
 Low education13.8 (21)13.6 (6)11.7 (9)19.4 (6)0.58
Lupus-specific and general health
 Lupus duration15.6±9.414.6±10.115.2±8.218.3±11.00.21
 Oral steroids46.0 (69)31.8 (14)46.1 (35)66.7 (20)0.01
  Oral steroid, mg/day3.9±5.93.6±7.23.4±4.85.5±6.30.27
 SLE activity4.4±2.82.6±2.24.8±2.56.0±3.0<0.0001
 SLAQ12.8±7.47.1±5.213.8±6.518.4±6.9<0.0001
 BILD2.1±2.01.2±1.22.1±2.03.2±2.4<0.0001
 Pain42.0±10.950.7±9.739.9±9.434.9±7.7<0.0001
 Obese (BMI ≥30 kg/m2)30.3 (44)16.7 (7)34.3 (25)40.0 (12)0.06
 Smoking0.41
  Current6.0 (9)6.8 (3)5.3 (4)6.5 (2)
  Former31.8 (48)36.4 (16)25.0 (19)41.9 (13)
  • SLE activity=self-reported on a 0 (inactive) to 10 (extremely active) scale.

  • Note: Tabled values are mean±SD or % (n).

  • *From analysis of variance or χ2 analysis comparing frailty classifications.

  • BMI, body mass index; BILD, Brief Index of Lupus Damage.43 ,44 Possible score range 0–46; higher scores reflect greater disease damage; SLAQ, Systemic Lupus Activity Questionnaire.29 ,30 Possible score range 0–44; higher scores reflect greater disease activity.