SLE-related single nucleotide polymorphisms (SNPs) and ORs for diffuse large B-cell lymphoma (DLBCL) in European Caucasians in InterLymph data
| Gene | Chromosome | SNP | Allele* DLBCL SLE ref. | DLBCL OR | DLBCL 95% CI | p Value* DLBCL | |
|---|---|---|---|---|---|---|---|
| CD40 | 20 | rs4810485 | T | T | C | 1.088 (1.017 to 1.162) | 0.013355 |
| HLA | 6 | rs1270942 | G | G | A | 1.171 (1.010 to 1.357) | 0.036172 |
| TNFSF4 | 1 | rs2205960 | A | A | G | 1.074 (0.998 to 1.156) | 0.054899 |
| IRF5 | 7 | rs12537284 | A | A | G | 1.081 (0.992 to 1.179) | 0.076450 |
| ILI10 | 1 | rs3024505 | A | A | G | 1.102 (0.898 to 1.353) | 0.352319 |
| BANK1 | 4 | rs10516487 | A | A | G | 1.035 (0.969 to 1.106) | 0.303231 |
| Mir146a | 5 | rs57095329 | G | G | A | 1.020 (0.756 to 1.377) | 0.896089 |
| ITGAM | 16 | rs9888739 | T | T | C | 1.008 (0.923 to 1.102) | 0.851519 |
| IFIH1 | 2 | rs1990760 | T | T | C | 1.037 (0.978 to 1.101) | 0.223359 |
| TNFAIP3 | 6 | rs7749323 | A | A | G | 1.053 (0.884 to 1.253) | 0.564425 |
| NCF2 | 1 | rs17849502 | T | G | G | 1.050 (0.892 to 1.236) | 0.554699 |
| STAT4 | 2 | rs7582694 | G | C | C | 1.110 (0.977 to 1.260) | 0.108048 |
| PTPN22 | 1 | rs2476601 | G | A | A | 1.043 (0.937 to 1.161 | 0.441704 |
| TYK2 | 19 | rs280519 | G | A | A | 1.016 (0.959 to 1.077) | 0.582604 |
| PHRF1/IRF7/KIAA1542 | 11 | rs4963128 | C | T | T | 1.018 (0.956 to 1.085) | 0.570646 |
| CD44 | 11 | rs507230 | A | G | G | 1.000 (0.941 to 1.062) | 0.987988 |
| XKR6 | 8 | rs6985109 | A | G | G | 1.040 (0.981 to 1.103) | 0.187826 |
| JAZF1 | 7 | rs849142 | C | T | T | 1.012 (0.903 to 1.134) | 0.836267 |
| UBE2L3 | 22 | rs463426 | C | G | T | 1.060 (0.938 to 1.197) | 0.349982 |
| BLK | 8 | rs7812879 | C | A | T | 1.058 (0.956 to 1.172) | 0.276113 |
| FCGR2A, FCGR3B | 1 | rs1801274 | G | T | A | 1.023 (0.913 to 1.147) | 0.693045 |
| IKZF1 | 7 | rs4917014 | G | C | T | 1.020 (0.916 to 1.138) | 0.710394 |
| LYN | 8 | rs7829816 | G | C | A | 1.031 (0.959 to 1.107) | 0.411987 |
| TNIP1 | 5 | rs10036748 | T | G | C | 1.015 (0.950 to 1.085) | 0.652213 |
| IRF8 | 16 | rs2280381 | T | A | C | 1.096 (0.933 to 1.287) | 0.265341 |
| ATG5 | 6 | rs548234 | T | G | C | 1.033 (0.936 to 1.140) | 0.518828 |
| PXK | 3 | rs6445975 | T | C | G | 1.011 (0.945 to 1.083) | 0.743076 |
| IL2/IL21 | 4 | rs907715 | T | G | C | 1.033 (0.967 to 1.104) | 0.339144 |
*With 28 comparisons, an α of 0.05 would correspond to a Bonferroni-corrected p value of 0.0018.