Table 1

Demographic characteristics of the study population

Complete respondersPartial respondersNon-responders
Patients, n (%)32 (29)37 (34)41 (37)
Age (years)32 (28–35)35 (29–38)31 (29–34)
Sex (female/male)31/135/238/3
Immunosuppressive agents (n)
 Cyclophosphamide6811
 Mycophenolate mofetil181114
 Mycophenolate sodium1128
 Tacrolimus667
 Azathioprine101
International Society of Nephrology/Renal Pathology Society (ISN/RPS) 2003 classification (n=76)
 III or III+V415
 IV or IV+V152019
 V345
Activity index (n=40)6.3 (3.6–9.1)10.4 (6.8–14.1)10.6 (3.6–9.1)
Chronicity index (n=40)1.9 (0.8–3.0)2.2 (0.7–3.7)3.4 (2.3–4.5)
Urinary protein to creatinine ratio (g/g)3.3 (2.5–4.2)6.2 (4.8–7.7)5.5 (3.8–7.2)
Serum creatine (mg/dL)0.9 (0.78–0.99)1.0 (0.84–1.08)0.9 (0.78–0.99)
C3 (mg/dL)83 (41–448)95 (35–773)83 (50–112)
Anti-dsDNA (IU)335 (151–518)461 (255–668)484 (0–1013
Serum albumin (g/dL)2.8 (2.5–3.2)2.9 (2.6–3.2)2.7 (2.4–3.0)
uTWEAK (pg/mgCr)0.58 (0.36–0.81)2.18 (0.78–3.58)1.11 (0.65–1.58)
  • Continuous variables presented as the mean (95% CI).

  • uTWEAK, urine TWEAK.