Risk of HCQ retinal toxicity (univariate)
| No n (%) | Yes n (%) | p | P for Trend | |
|---|---|---|---|---|
| Characteristic | ||||
| Sex | 0.1029 | |||
| Female | 475 (96.2) | 19 (3.8) | ||
| Male | 39 (90.7) | 4 (9.3) | ||
| Ethnicity | 0.3804 | |||
| White | 238 (94.4) | 14 (5.6) | ||
| Black | 215 (96.4) | 8 (3.6) | ||
| Other | 61 (98.4) | 1 (1.6) | ||
| Age | <0.0001 | <0.0001 | ||
| <45 | 215 (99.5) | 1 (0.5) | ||
| 45–59 | 175 (95.6) | 8 (4.4) | ||
| 60+ | 124 (89.9) | 14 (10.1) | ||
| HCQ max | 0.0340 | 0.0143 | ||
| 1 (0 to 1182) | 161 (98.8) | 2 (1.2) | ||
| 2 (1183 to 1752) | 157 (95.2) | 8 (4.8) | ||
| 3 (1753 to 6281) | 153 (93.3) | 11 (6.7) | ||
| HCQ duration | 0.0006 | 0.0002 | ||
| 1 (0 to 8 years) | 158 (98.8) | 2 (1.2) | ||
| 2 (9 to 15 years) | 139 (97.2) | 4 (2.8) | ||
| 3 (16 to 48 years) | 154 (90.1) | 17 (9.9) | ||
| BMI | 0.1701 | 0.0160 | ||
| <20 | 50 (98.0) | 1 (2.0) | ||
| 20–25 | 171 (97.7) | 4 (2.3) | ||
| 25–30 | 159 (95.2) | 8 (4.8) | ||
| 30–35 | 76 (95.0) | 4 (5.0) | ||
| 35+ | 58 (90.6) | 6 (9.4) | ||
| HTN Ever | 0.0020 | |||
| Yes | 276 (93.2) | 20 (6.8) | ||
| No | 238 (98.8) | 3 (1.2) | ||