Table 2

Number (%) of patients with complement activation before and normalisation after rituximab+belimumab

C4dC4C3Total
Complement activation
 C4d149 (64%)13 (93%)14/15 (93%)
 C49 (100%)98 (89%)9/15 (60%)
 C313 (100%)9 (69%)1313/15 (87%)
Complement normalisation
 C4d66 (100%)4 (67%)6/14 (43%)
 C43 (50%)64 (67%)6/9 (67%)
 C33 (50%)6 (100%)66/13 (46%)
  • SLEDAI, Systemic Lupus Erythematosus Disease Activity Index.