Logistics regression model of biologic perceptions and preferences, adjusted by sociodemographic characteristics
| Ever on biologics (n=543) | Family/friends on biologics (n=544) | Concern about potential complications from biologics (n=513) | Biologics work differently by race/ethnicity (n=520) | Biologics are helpful in treating lupus (n=515) | Biologic treatment decision based on modality (n=534) | |||||||
| Variable | OR | P value | OR | P value | OR | P value | OR | P value | OR | P value | OR | P value |
| Race (black vs white) | 0.65 (0.30–1.40) | 0.27 | 0.39 (0.17–0.90) | 0.028 | 2.15 (1.31–3.53) | 0.0023 | 1.32 (0.71–2.46) | 0.38 | 0.63 (0.38–1.06) | 0.082 | 1.19 (0.70–2.04) | 0.52 |
| Age at survey (per 5 years↑) | 0.86 (0.73–1.00) | 0.047 | 1.01 (0.84–1.21) | 0.91 | 1.08 (0.98–1.18) | 0.11 | 0.98 (0.88–1.08) | 0.65 | 0.96 (0.87–1.05) | 0.38 | 0.91 (0.82–1.00) | 0.052 |
| Disease duration (per 5 years↑) | 0.85 (0.68–1.05) | 0.14 | 1.14 (0.93–1.41) | 0.22 | 0.97 (0.87–1.09) | 0.59 | 0.96 (0.84–1.10) | 0.58 | 0.95 (0.84–1.08) | 0.43 | 0.97 (0.85–1.10) | 0.62 |
| Disease activity (per 3 units↑) | 1.03 (0.92–1.15) | 0.58 | 1.13 (0.99–1.29) | 0.069 | 0.98 (0.92–1.05) | 0.58 | 0.95 (0.88–1.03) | 0.19 | 0.98 (0.92–1.06) | 0.65 | 1.00 (0.93–1.07) | 0.99 |
| Education (per 3 years↑) | 1.17 (0.82–1.67) | 0.38 | 1.25 (0.86–1.83) | 0.24 | 0.85 (0.68–1.05) | 0.13 | 0.97 (0.76–1.25) | 0.84 | 1.16 (0.93–1.46) | 0.19 | 0.95 (0.75–1.21) | 0.7 |
| Gender (female vs male) | 1.05 (0.28–3.89) | 0.94 | 0.52 (0.14–1.94) | 0.33 | 2.98 (1.32–6.69) | 0.0083 | 1.57 (0.61–4.08) | 0.35 | 0.51 (0.24–1.10) | 0.086 | 0.94 (0.42–2.10) | 0.88 |
| Below poverty (compared with those not below poverty) | 0.59 (0.25–1.44) | 0.25 | 0.59 (0.20–1.79) | 0.35 | 1.23 (0.74–2.04) | 0.43 | 0.59 (0.33–1.06) | 0.075 | 0.97 (0.56–1.68) | 0.93 | 0.72 (0.41–1.27) | 0.26 |
| Damage (reference: no) mild damage | 1.91 (0.60–6.06) | 0.19 | 1.71 (0.45–6.43) | 0.14 | 0.36 (0.18–0.70) | 0.0068 | 0.88 (0.43–1.79) | 0.72 | 1.12 (0.57–2.21) | 0.42 | 2.29 (1.12–4.71) | 0.032 |
| Severe damage | 1.32 (0.38–4.53) | 0.91 | 0.80 (0.19–3.40) | 0.34 | 0.44 (0.22–0.89) | 0.21 | 0.65 (0.30–1.39) | 0.18 | 0.87 (0.42–1.78) | 0.43 | 1.87 (0.87–4.03) | 0.43 |
| Insurance (reference: private) no insurance | 0.28 (0.03–2.40) | 0.1 | 0.65 (0.12–3.44) | 0.9 | 0.90 (0.42–1.94) | 0.96 | 2.21 (0.93–5.25) | 0.39 | 0.95 (0.40–2.27) | 0.23 | 0.93 (0.42–2.06) | 0.58 |
| Medicare | 3.61 (1.33–9.83) | 0.0015 | 0.70 (0.24–2.04) | 0.99 | 0.59 (0.33–1.07) | 0.034 | 1.90 (0.93–3.87) | 0.65 | 1.68 (0.87–3.23) | 0.32 | 0.75 (0.40–1.42) | 0.79 |
| Medicaid | 1.15 (0.36–3.75) | 0.81 | 0.52 (0.14–1.95) | 0.52 | 1.16 (0.60–2.24) | 0.16 | 2.07 (0.96–4.48) | 0.4 | 2.16 (1.07–4.38) | 0.027 | 0.57 (0.28–1.16) | 0.13 |
| Employed | 1.18 (0.48–2.88) | 0.72 | 0.69 (0.26–1.81) | 0.45 | 0.93 (0.56–1.55) | 0.79 | 1.03 (0.56–1.90) | 0.93 | 1.07 (0.61–1.88) | 0.8 | 1.12 (0.65–1.93) | 0.67 |
| Married | 1.01 (0.48–2.12) | 0.98 | 0.64 (0.28–1.48) | 0.3 | 0.79 (0.52–1.22) | 0.29 | 0.71 (0.42–1.19) | 0.19 | 0.90 (0.56–1.43) | 0.65 | 1.02 (0.64–1.63) | 0.92 |
| (Hosmer and Lemeshow goodness-of-fit test) | – | 0.32 | – | 0.89 | – | 0.67 | – | 0.50 | – | 0.17 | – | 0.86 |
’Don’t Know’ or ‘Neutral’ responses are included in the ‘NO’ group.