Table 2

Baseline characteristics of subjects with and without missing SRI-5 data at 52 weeks

VariableMissing SRI-5 at 52 weeksP value
Yes (n=69)No (n=210)
MMF, n (%)19 (27.5)41 (19.5)0.16
White race, n (%)42 (60.9)119 (56.7)0.54
Age (years)36.9 (12.31)39.0 (11.82)0.21
Disease duration (years)4.68 (5.81)4.90 (7.71)0.60
Prednisone dose (mg/day)10.0 (12.5)10.0 (10.0)0.15
BILAG score15.75 (8.38)14.75 (7.11)0.33
SLEDAI10.68 (4.31)10.60 (3.70)0.89
PGA46.50 (19.59)47.09 (16.25)0.82
White cell count (×109/L)5.68 (2.51)5.90 (2.49)0.53
Lymphocytes (×109/L)1.14 (0.52)1.24 (0.61)0.23
Neutrophils (×109/L)3.71 (2.61)3.64 (2.46)0.92
CD19 (%)11.45 (13.5)9.10 (11.1)0.14
Haemoglobin (g/L)122.0 (13.4)123.7 (15.1)0.41
C3 (g/L)0.97 (0.36)1.00 (0.31)0.61
C4 (g/L)17.2 (15.7)15.1 (12.3)0.39
Anti-dsDNA (IU/mL)120.5 (245.5)69.0 (288.0)0.99
IgG (g/L)14.99 (5.21)15.70 (5.49)0.35
IgM (g/L)0.91 (0.74)0.99 (0.78)0.27
IgA (g/L)2.63 (1.69)2.97 (1.56)0.12
Anti-SM (U/mL)5.5 (21.5)5.5 (2.8)0.51
Anti-RNP (U/mL)5.5 (82.0)5.5 (88.0)0.25
Anti-SSA/Ro (U/mL)5.5 (128.5)5.5 (102.0)0.77
Anti-SSB/La (U/mL)13.75 (29.03)21.96 (38.52)0.06
Protein to creatinine ratio0.07 (0.12)0.06 (0.11)0.49
  • Values are mean (SD) or median (IQR) depending on distribution of the data.

  • P values were based on t-tests or Wilcoxon tests for continuous variables, and χ2 tests for categorical variables.

  • anti-dsDNA, anti-double stranded DNA; anti-RNP, anti-ribonucleoprotein; anti-SM, anti-Smith ; anti-SSA/Ro, anti-Sjögren’s syndrome related antigen A; anti-SSB/La, anti-Sjögren's syndrome type B; BILAG, British Isles Lupus Assessment Group; MMF, mycophenolate mofetil; PGA, Physician Global Assessment; SLEDAI, SLE Disease Activity Index; SRI-5, SLE Responder Index-5.