HR (95% CI) | P value | |
Age (per decade) | 1.39 (1.22 to 1.60) | <0.0001 |
Male (vs female) | 1.48 (0.95 to 2.32) | 0.084 |
Systolic blood pressure (per 10 mm Hg, treated) | 1.23 (1.10 to 1.38) | 0.0003 |
Systolic blood pressure (per 10 mm Hg, not treated) | 1.21 (1.07 to 1.37) | 0.0029 |
Current or past smoking | 1.76 (1.29 to 2.40) | 0.0004 |
Total serum cholesterol >140 mg/dL | 2.35 (1.15 to 4.80) | 0.020 |
Diabetes mellitus | 2.40 (1.66 to 3.49) | <0.0001 |
SLEDAI (per unit increase) | 1.07 (1.00 to 1.14) | 0.041 |
History of lupus anticoagulant | 1.71 (1.23 to 2.37) | 0.0013 |
Low mean C3 (<79) | 2.35 (1.62 to 3.42) | <0.0001 |
*The broad definition includes coronary death, myocardial infarction, coronary insufficiency, angina, ischaemic stroke, haemorrhagic stroke, transient ischaemic attack, peripheral artery disease, heart failure.
SLEDAI, SLE Disease Activity Index.