Table 2

Association between predictors measured in the first year of follow-up and subsequent risk of a cardiovascular event based on the broad definition of a cardiovascular event*

HR (95% CI)P value
Age (per decade)1.39 (1.22 to 1.60)<0.0001
Male (vs female)1.48 (0.95 to 2.32)0.084
Systolic blood pressure (per 10 mm Hg, treated)1.23 (1.10 to 1.38)0.0003
Systolic blood pressure (per 10 mm Hg, not treated)1.21 (1.07 to 1.37)0.0029
Current or past smoking1.76 (1.29 to 2.40)0.0004
Total serum cholesterol >140 mg/dL2.35 (1.15 to 4.80)0.020
Diabetes mellitus2.40 (1.66 to 3.49)<0.0001
SLEDAI (per unit increase)1.07 (1.00 to 1.14)0.041
History of lupus anticoagulant1.71 (1.23 to 2.37)0.0013
Low mean C3 (<79)2.35 (1.62 to 3.42)<0.0001
  • *The broad definition includes coronary death, myocardial infarction, coronary insufficiency, angina, ischaemic stroke, haemorrhagic stroke, transient ischaemic attack, peripheral artery disease, heart failure.

  • SLEDAI, SLE Disease Activity Index.