1- Baseline patient characteristics (n =10 ) | |||||
Age (years) | 22.3 years | ||||
Female Sex | 8 (80%) | ||||
SLE diagnosis duration | 3.8 years | ||||
History of hypertension | 2 (20%) | ||||
History of DM | 0 (0%) | ||||
Previous cardiac history | 0 (0%) | ||||
2- Clinical data | |||||
Onset of LM | LN and LM | LN preceding LM | |||
6 (60%) | 4 (40%) | ||||
Clinical presentation | Cardiogenic shock | Acute heart failure | Syncope | ||
4 (40%) | 5 (50%) | 1 (10%) | |||
3- Laboratory and renal biopsy data | |||||
CBC | HB level | 8.7 gm/dl | |||
Wbcs count | 6.1 10^3/μl | ||||
Platelets count | 199 10^3/μl | ||||
Creatinine level | 2.6 mg/dl | ||||
Protein: Creatinine ratio | 3.6 mg/mg | ||||
Patients with renal biopsy | 5 (50%) | ||||
Class III | Class IV | ||||
1 (20%) | 4 (80%) | ||||
4- Baseline Echocardiography | |||||
LVEF | 26.3% | ||||
ESD | 46.1 mm | ||||
EDD | 56.3 mm | ||||
Global hypokinesia | 9 (90%) | ||||
Mitral regurgitation | 10 (100%) | ||||
Tricuspid regurgitation | 8 (80%) | ||||
Pericardial effusion | 7 (70%) | ||||
Pulmonary hypertension | 4 (40%) | ||||
5- Management | |||||
Pulse steroids | 10 (100%) | ||||
IV cyclophosphamide | 7 (70%) | ||||
mycophenolate mofetil | 3 (30%) | ||||
Immunoadsorption | 1 (10%) | ||||
6- Follow-up echocardiography after 3 months | |||||
LVEF | 42.8% | ||||
ESD | 38.9 mm | ||||
EDD | 52 mm | ||||
7- Outcomes | |||||
Complete recovery | 4 (40%) | ||||
Partial improvement | 2 (20%) | ||||
Mortality | 3 (30%) |
Data is represented as mean or number (%)