Table 6

FACIT-F: responsiveness and ability to detect change in SLE (within-group)

Reference	Anchor (clinical severity measure)	Findings
Reference	Anchor (clinical severity measure)	SRI responder mean	SRI non-responder mean	P value
Furie et al35	SRI responder	5.2	3.0	<0.001
		Improved	Unchanged	Worsened
		Mean (SD), ES, p value	Mean (SD), ES, p value	Mean (SD), ES, p value
Lai et al52	BILAG musculoskeletal change	7.1 (10.7), 0.66, <0.001	3.3 (11.0), 0.30, 0.004	2.5 (11.6), 0.22, 0.617
	BILAG general change	8.2 (11.9), 0.69, <0.001	4.2 (10.2), 0.41, <0.001	0.0 (9.1), 0.00, 1.00
	Patient global assessment of change	10.5 (12.9), 0.82, <0.001	3.1 (7.8), 0.40, <0.001	−3.6 (6.7), –0.53, p<0.016

BILAG, British Isles Lupus Assessment Group; ES, effect size; FACIT-F, Functional Assessment of Chronic Illness Therapy-Fatigue Scale; SRI, SLE Responder Index.