Baseline features as predictors for damage accrual
| Baseline | Univariable* | CI | Multivariable* | CI |
| Severity at diagnosis (mild vs moderate/severe) | 1.26 | 0.86 to 1.84 | ||
| Transition | 6.88 | 4.28 to 11.06 | 5.66 | 2.74 to 11.67 |
| Age at diagnosis | 1.00 | 0.99 to 1.01 | 1.05 | 1.02 to 1.08 |
| Disease duration | 1.11 (per year) | 1.08 to 1.14 | 1.15 | 1.09 to 1.22 |
| Sex (m/f) | 1.41 | 0.75 to 2.65 | ||
| Late-onset SLE | 0.97 | 0.61 to 1.55 | ||
| cSLE | 0.89 | 0.48 to 1.64 | ||
| Fever | 1.62 | 1.05 to 2.51 | ||
| Leucopenia | 0.63 | 0.39 to 1.01 | ||
| Obesity | 2.00 | 1.29 to 3.11 | ||
| Hypertension | 2.23 | 1.40 to 3.54 | ||
| Dyslipidaemia | 2.10 | 1.25 to 3.51 | ||
| aPL | 1.54 | 0.95 to 2.50 | 2.22 | 1.09 to 4.53 |
| Anti-dsDNA | 1.33 | 0.89 to 1.99 | ||
| Low complement | 1.10 | 0.73 to 1.66 |
Values in bold represent associations that reached statistical significance (p< 0.05).
*OR for SLICC Damage Index.
anti-dsDNA, anti-double-stranded DNA; aPL, antiphospholipid antibodies; cSLE, childhood-onset SLE; m/f, male/female; SLICC, Systemic Lupus International Collaborating Clinics.