Baseline features as predictors of phenotype transition from mild to moderate disease
| Transition from mild to moderate disease | ||||
| Baseline | Univariable | CI | Multivariable | CI |
| SDI (0 vs ≠0) | 0.23 | 0.02 to 1.92 | ||
| Age at diagnosis | 0.97 | 0.95 to 0.99 | 1.02 | 0.97 to 1.06 |
| Disease duration | 1.07 (per year) | 1.03 to 1.11 | 1.05 | 1.00 to 1.11 |
| Sex (m/f) | 0.54 | 0.14 to 2.08 | 0.47 | 0.08 to 2.76 |
| Late-onset SLE | 0.2 | 0.09 to 0.63 | 0.36 | 0.09 to 1.46 |
| Acute cutaneous lupus | 0.65 | 0.36 to 1.24 | ||
| Leucopenia | 1.02 | 0.52 to 1.99 | ||
| Fever | 2.04 | 0.88 to 4.74 | ||
| ANA | 4.3 | 0.51 to 35.67 | ||
| dsDNA | 2.72 | 1.44 to 5.15 | 2.39 | 1.07 to 5.32 |
| Low complement | 1.36 | 0.71 to 2.59 | ||
| Anti-Sm | 0.49 | 0.05 to 4.8 | ||
Values in bold represent associations that reached statistical significance (p< 0.05).
anti-Sm, anti-Smith; dsDNA, double-stranded DNA; m/f, male/female; SDI, SLICC Damage Index; SLICC, Systemic Lupus International Collaborating Clinics.