Variables at baseline, pre-propensity and post-propensity score matching for patients with ≥1 year of follow-up from pooled LTE and Toronto Lupus Cohort datasets
Variable | Pre-propensity score matching (n=1541) | Post-propensity score matching (n=646) | ||||
Mean | % Bias | Mean | % Bias | |||
Belimumab | Standard therapy | Belimumab | Standard therapy | |||
Age | 38.782 | 36.735 | 16.2 | 38.108 | 37.416 | 5.4 |
Age squared | 1634.0 | 1538.5 | 9.0 | 1611.1 | 1566.9 | 4.2 |
Female | 0.942 | 0.885 | 20.4 | 0.926 | 0.913 | 4.5 |
Race | ||||||
Black | 0.075 | 0.150 | −24.1 | 0.115 | 0.108 | 2.0 |
Asian/other | 0.457 | 0.301 | 32.7 | 0.337 | 0.362 | −5.2 |
SLE duration | 6.737 | 6.358 | 5.5 | 7.061 | 6.803 | 3.6 |
Hypertension | 0.400 | 0.383 | 3.3 | 0.412 | 0.402 | 1.9 |
Dyslipidaemia | 0.128 | 0.471 | −80.7 | 0.279 | 0.282 | −0.7 |
Proteinuria | 0.169 | 0.346 | −41.3 | 0.245 | 0.263 | −4.3 |
ACR criteria | 5.971 | 5.674 | 21.6 | 5.901 | 5.892 | 0.7 |
Baseline SLEDAI | 8.273 | 10.100 | −39.8 | 9.105 | 9.046 | 1.4 |
Corticosteroid use | 0.859 | 0.639 | 52.5 | 0.715 | 0.743 | −6.3 |
Antimalarial use | 0.669 | 0.593 | 15.8 | 0.656 | 0.628 | 5.8 |
Immunosuppressive use | 0.472 | 0.372 | 20.4 | 0.399 | 0.409 | −1.9 |
Baseline SDI=1 | 0.241 | 0.150 | 22.9 | 0.235 | 0.195 | 9.8 |
Baseline SDI≥2 | 0.177 | 0.103 | 21.3 | 0.133 | 0.139 | −1.8 |
ACR, American College of Rheumatology; LTE, long-term extension; SDI, SLICC/ACR Damage Index; SLE, systemic lupus erythematosus;; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index; SLICC, Systemic Lupus International Collaborating Clinics.