Intertest agreement of baseline ANA patterns between HEp-2 cells and ML for 961 patients
| Disease | Most common HEp2 pattern (%) | Most common ML pattern (%) | Agreement pattern (%) | Weighted kappa | SE | P value |
| SLE | Diffuse (38.8) | Specked (37.1) | 90.4 | 0.50 | 0.04 | <0.0001 |
| DM/PM | Diffuse (30.8) Speckled (30.8) | Diffuse (45.5) Speckled (45.5) | 78.8 | 0.35 | 0.18 | 0.02 |
| RA | Diffuse (51.9) | Diffuse (52.3) | 88.8 | 0.39 | 0.07 | <0.0001 |
| SS | Speckled (54.4) | Speckled (54.3) | 90.5 | 0.61 | 0.13 | <0.0001 |
| MCTD | Speckled (60.0) | Speckled (56.5) | 98.3 | 0.93 | 0.17 | <0.0001 |
| SSc | Speckled (34.0) | Speckled (34.3) | 83.4 | 0.44 | 0.11 | <0.0001 |
| APS | Diffuse (60.0) | Speckled (55.6) | 83.3 | 0.47 | 0.25 | 0.03 |
| Controls | Speckled (45.2) | Speckled (50.0) | 83.3 | 0.46 | 0.14 | <0.001 |
| Overall | Diffuse (37.8) | Speckled (37.3) | 91.6 | 0.48 | 0.03 | <0.0001 |
APS, antiphospholipid syndrome; DM/PM, dermatopolymyositis; MCTD, mixed connective tissue disease; ML, mouse liver; RA, rheumatoid arthritis; SS, Sjögren’s syndrome; SSc, systemic sclerosis.