Model | Observed data | Imputed analysis | ||
Per cent change (95% CI) | P value | Per cent change (95% CI) | P value | |
Unadjusted Poisson regression model (recessive) | ||||
0RV or 1RV vs 2RV | 81.3 (12.3 to 192.7) | 0.01 | 78.4 (10.6 to 187.8) | 0.02 |
Poisson regression model (recessive) to adjusted for SLEDAI | ||||
0RV or 1RV vs 2RV | 72.2 (6.5 to 178.3) | 0.03 | 69.5 (4.9 to 173.8) | 0.03 |
Average SLEDAI | 4.7 (1.9 to 7.7) | 0.001 | 4.7 (1.8 to 7.6) | 0.001 |
Poisson regression model (recessive) to adjusted for SLEDAI and duration of SLE | ||||
0RV or 1RV vs 2RV | 80.8 (11 to 194.4) | 0.01 | 77.7 (9.2 to 189.1) | 0.02 |
Average SLEDAI | 4.2 (1.1 to 7.4) | 0.008 | 4.2 (1.1 to 7.3) | 0.008 |
Disease duration | 1.5 (−6.5 to 10.2) | 0.72 | 1.5 (−6.5 to 10.1) | 0.73 |
Per cent change (rate of change) and 95% CI for the unadjusted Poisson regression model, as well as two adjusted Poisson regression models are shown. Results are shown for the complete case analysis (observed data, excluding missing values) and following multiple imputations, assuming missing at random (imputed analysis).
APOL1, apolipoprotein L1; RV, risk variant; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index.;