Correlation between analyte concentrations (PBMC and plasma) and progression of non-calcified and calcified plaque
| Non-calcified plaque | Calcified plaque | ||||||
| Progressor (n=6) | Regressor (n=2) | P value | Progressor (n=4) | Regressor (n=4) | P value | ||
| PBMC (pmol/ million cells) | Hcy | 389 (226) | 282.9 (139.1) | 0.56 | 269.8 (140) | 455.2 (233.8) | 0.22 |
| Methionine | 43 883 (21178.1) | 29 713.5 (9066.9) | 0.41 | 41 378.2 (17555.8) | 39 303 (23753.7) | 0.89 | |
| Cystathionine | 79.1 (53.4) | 102.8 (79.3) | 0.64 | 73.8 (51) | 96.3 (64.8) | 0.60 | |
| SAH | 725.8 (299.4) | 667.8 (328.1) | 0.82 | 704.4 (236.3) | 718.3 (362) | 0.95 | |
| SAM | 1620.5 (389.9) | 2397.7 (958.4) | 0.12 | 1804.4 (390.6) | 1825.2 (841.8) | 0.96 | |
| 5m-THF | 548.5 (447.9) | 599.2 (153.2) | 0.88 | 590.2 (418) | 532.2 (408) | 0.83 | |
| Plasma (nM) | Hcy | 16 657.3 (623.5) | 15 871.7 (2427.9) | 0.73 | 16 271.3 (1519) | 16 650.4 (720) | 0.67 |
| Methionine | 19 272.2 (10522.1) | 19 303 (7588.4) | 0.99 | 21 381 (3332.1) | 17 178.7 (13447.8) | 0.58 | |
| Cystathionine | 177.2 (62.9) | 101.2 (10.6) | 0.16 | 154.4 (86.3) | 161.9 (45.1) | 0.88 | |
| SAH | 53.1 (18.5) | 41.9 (12.7) | 0.46 | 53.1 (23.4) | 47.5 (10.8) | 0.68 | |
| SAM | 216.4 (99.1) | 276.7 (69.7) | 0.46 | 288.6 (93.3) | 174.3 (48.8) | 0.07 | |
Hcy, homocysteine; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine.