Table 2

Average concentration of PBMC and plasma analytes in patients with SLE patients and controls

PBMC (pmol/million cells)Plasma (nM)
ControlPatientP valueControlPatientP value
Homocysteine1.57 (SD=0.6)1.7 (SD=0.92)0.6810 807.5 (SD=3033.5)16 453.4 (SD=1764.4)0.00008
Methionine286.8 (SD=197.9)210 (SD=103.1)0.2924 930.56 (SD=5099.2)17 877.6 (SD=9216.53)0.048
Cystathionine0.13 (SD=0.07)0.65 (SD=0.774)0.04997.4 (SD=32)180.2 (SD=84)0.009
SAH2.46 (SD=0.86)3.53 (SD=1.36)0.04930.31 (SD=10.74)47.78 (SD=16.4)0.01
SAM5.04 (SD=1.74)8.51 (SD=2.94)0.005119.67 (SD=20.1)229.62 (SD=91.27)0.001
5m-THF0.88 (SD=0.48)3.07 (SD=1.96)0.005N/AN/A
  • 5m-THF, 5-methyltetrahydrofolate; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine.