PBMC (pmol/million cells) | Plasma (nM) | |||||
Control | Patient | P value | Control | Patient | P value | |
Homocysteine | 1.57 (SD=0.6) | 1.7 (SD=0.92) | 0.68 | 10 807.5 (SD=3033.5) | 16 453.4 (SD=1764.4) | 0.00008 |
Methionine | 286.8 (SD=197.9) | 210 (SD=103.1) | 0.29 | 24 930.56 (SD=5099.2) | 17 877.6 (SD=9216.53) | 0.048 |
Cystathionine | 0.13 (SD=0.07) | 0.65 (SD=0.774) | 0.049 | 97.4 (SD=32) | 180.2 (SD=84) | 0.009 |
SAH | 2.46 (SD=0.86) | 3.53 (SD=1.36) | 0.049 | 30.31 (SD=10.74) | 47.78 (SD=16.4) | 0.01 |
SAM | 5.04 (SD=1.74) | 8.51 (SD=2.94) | 0.005 | 119.67 (SD=20.1) | 229.62 (SD=91.27) | 0.001 |
5m-THF | 0.88 (SD=0.48) | 3.07 (SD=1.96) | 0.005 | N/A | N/A |
5m-THF, 5-methyltetrahydrofolate; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine.