Table 2

Pathology findings in patients with SLE with high or low 2019 criteria score

FindingHigh 2019 criteria score (n=59)Low 2019 criteria score (n=60)*Nominal p value
Light microscopy
ISN/RPS 2003 class
 Ⅱ1 (1.69%)4 (6.67%)0.034
 Ⅲ/Ⅳ42 (71.19%)29 (48.33%)
 Ⅲ/Ⅳ+V8 (13.56%)8 (13.33%)
 V8 (13.56%)19 (31.67%)
Sclerotic glomeruli, median (IQR), %0 (0, 7.80)0 (0, 4.16)0.713
Crescents, median (IQR), %2.56 (0,16.67)0 (0, 5.60)0.061
Capillary necrosis
 Absent56 (94.92%)54 (90.0%)0.311
 Existed3 (5.08%)6 (10.0%)
Mesangial hypercellularity
 Mild42 (71.19%)40 (66.67%)0.252
 Moderate15 (25.42%)20 (33.33%)
 Severe2 (3.39%)0
Interstitial infiltrates
 0~25%54 (91.53%)52 (86.67%)0.063
 25%~50%5 (8.47%)3 (5.00%)
 >50%05 (8.33%)
Immunofluorescence microscopy
IgA
 09 (15.25%)14 (23.33%)0.194
 1+10 (16.95%)17 (28.33%)
 2+22 (37.29%)15 (25.0%)
 ≥3+18 (30.51%)14 (23.33%)
IgM
 012 (20.34%)11 (18.33%)0.918
 1+13 (22.03%)15 (25.0%)
 2+27 (45.76%)25 (25.0%)
 ≥3+7 (11.86%)9 (15.0%)
IgG
 042 (71.19%)43 (71.67%)0.096
 1+6 (10.17%)13 (21.67%)
 2+10 (16.95%)3 (5.00%)
 ≥3+1 (1.69%)1 (1.67%)
C3
 08 (13.56%)17 (28.33%)0.162
 1+3 (5.08%)4 (6.67%)
 2+18 (30.51%)11 (18.33%)
 ≥3+30 (50.85%)28 (46.67%)
C4
 027 (45.76%)29 (48.33%)0.638
 1+17 (28.81%)20 (33.33%)
 2+13 (22.03%)8 (13.33%)
 ≥3+2 (3.39%)3 (5.00%)
C1q
 014 (23.73%)14 (23.33%)0.205
 1+7 (11.86%)16 (26.67%)
 2+25 (42.37%)21 (35.0%)
 ≥3+13 (22.03%)9 (15.0%)
AI3.83±0.312.73±0.250.007
CI2.53±0.152.77±0.210.343

  • P-values <0.05 were considered as significance and marked in bold.

  • *The data of pathology findings of one patient were absent.

  • AI, activity index; CI, chronicity index.