Table 1

Individual classification criterion as described by domain, classification criteria they belong to and underlying medical record data types used to identify each criterion

CriterionClassification criteria domainLupus classification criteriaUnderlying medical record data types
ACR 1997SLICC 2012EULAR/ACR 2019
Acute cutaneous lupusClinicalXXDiagnosis codes (ICD-9/10),
medications
AlopeciaClinicalXXDiagnosis codes (ICD-9/10)
Arthritis (synovitis)ClinicalXXXDiagnosis codes (ICD-9/10)
Chronic cutaneous lupusClinicalXXDiagnosis codes (ICD-9/10)
DeliriumClinicalXDiagnosis codes (ICD-9/10)
Discoid rashClinicalXDiagnosis codes (ICD-9/10)
FeverClinicalXDiagnosis codes (ICD-9/10)
Haematological disorderClinicalXDiagnosis codes (ICD-9/10),
laboratory results
Haemolytic anaemiaClinicalXXDiagnosis codes (ICD-9/10),
laboratory results
LeucopeniaClinicalXXDiagnosis codes (ICD-9/10),
laboratory results
Malar rashClinicalXDiagnosis codes (ICD-9/10),
medications
Neurological disorder (ACR)ClinicalXDiagnosis codes (ICD-9/10)
Neurological disorder (SLICC)ClinicalXDiagnosis codes (ICD-9/10)
Oral ulcersClinicalXXXDiagnosis codes (ICD-9/10)
PhotosensitivityClinicalXDiagnosis codes (ICD-9/10)
Renal disorder (ACR)ClinicalXDiagnosis codes (ICD-9/10),
laboratory results
Renal disorder (SLICC)ClinicalXDiagnosis codes (ICD-9/10),
laboratory results
Renal disorder (EULAR/ACR)ClinicalXLaboratory results
SeizureClinicalXDiagnosis codes (ICD-9/10)
SerositisClinicalXXXICD-9/10 codes,
procedure codes (CPT)
ThrombocytopeniaClinicalXXDiagnosis codes (ICD-9/10),
laboratory results
Anti-dsDNA AbImmunologicalXXLaboratory results
Antinuclear AbImmunologicalXXXLaboratory results
Antiphospholipid AbImmunologicalXXLaboratory results
Anti-Smith AbImmunologicalXXLaboratory results
Direct Coombs testImmunologicalXLaboratory results
Immunological disordersImmunologicalXDiagnosis codes (ICD-9/10),
laboratory results
Low complementImmunologicalXLaboratory results
C3ImmunologicalXLaboratory results
C4ImmunologicalXLaboratory results
  • ACR, American College of Rheumatology; CPT, current procedural terminology; EULAR, European League Against Rheumatism; ICD-9/10, International Classification of Diseases versions 9 and 10; SLICC, Systemic Lupus International Collaborating Clinics.