Table 3

Zero-order and partial correlations between emotional, haemodynamic and functional connectivity measured in the total sample of patients with NPSLE

	Anxiety		Anxiety controlling for age and depression
	Haemodynamic lead*	ICC*	Haemodynamic lead†	ICC†
R MFG (BA 46/9)	0.317	−0.654	<0.1	−0.572
L MFG (BA 46/9)	0.307	−0.294	<0.1	−0.337
R ACC (ΒΑ 32)	0.311	−0.178	0.164	<0.1
L Subgenual ACC	0.417	<0.1	0.221	<0.1
R lat. Orbitofrontal (ΒΑ 10)	0.595	−0.436	0.372	−0.260
R Amygdala	0.591	−0.196	0.524	−0.262
L Amygdala	0.249	−0.405	0.376	−0.273
	ROI-to-ROI connectivity‡
(R)ACC←→Amygdala	0.611		0.496
(R)med. Frontal gyrus←→MFG	−0.758		−0.652

	Depression		Depression controlling for age and anxiety
L ACC (ΒΑ 32)	<0.1	<0.1	<0.1
R Precuneus (ΒΑ 7)	<0.1	−0.131	<0.1
R lat. Orbitofrontal (ΒΑ 11)	0.590	<0.1	0.440	0.198
L lat. Orbitofrontal (ΒΑ 11)	0.502	<0.1	0.534	0.421
R med. Orbitofrontal (BA 11)	0.656	−0.438 L	0.562	−0.576
R med. Frontal gyrus (ΒΑ 9)	0.412	−0.318	0.241	−0.242
L med. Frontal gyrus (ΒΑ 10)	0.403 p	−0.236	0.271	−0.269
R Amygdala	0.377	−0.411	<0.1	−0.322
L Amygdala	<0.1	−0.434	−0.316	−0.266
	ROI-to-ROI connectivity‡
(R)ACC←→Amygdala	0.564		<1
(R)med. Frontal gyrus←→MFG	−0.562		<0.1

Haemodynamic lead: Percentage of voxels with negative TSA values within a given ROI. Note: all other pairwise connectivity measures: r<0.15.
*Correlations shown bold were significant at p<0.007.
†p<0.006.
‡p<0.002.
ACC, anterior cingulate cortex; lat., lateral; med., medial; MFG, middle frontal gyrus.