Table 1

Demographic and clinical characteristics of patients with NPSLE

Female31 (96.9%)
Age, mean (SD in years)47.8 (12.5)
Education, mean (SD in years)11.9 (3.7)
Disease duration, mean (SD in years)5.3 (5.2)
SLEDAI-2K, mean (SD)5.3 (4.4)
SLICC/ACR Damage Index (SDI), mean (SD)0.29 (0.5)
aPL (+)ve3 (9.4%)
Smoking13 (41.9%)
NPSLE syndrome
 Mood disorder9 (27.3%)
 Cognitive dysfunction6 (18.2%)
 Anxiety disorder5 (15.2%)
 Cerebrovascular disease4 (12.1%)
 Psychosis3 (9.1%)
 Cranial neuropathy2 (6.1%)
 Acute confusional state1 (3.0%)
 Seizures1 (3.0%)
 Myelopathy1 (3.0%)
 Polyneuropathy1 (3.0%)
HADS Anxiety, mean (SD)12.9 (4.6)
HADS Depression, mean (SD)10.3 (5.6)
HADS Anxiety ≥8 points21 (65.6%)
HADS Depression ≥8 points17 (53.1%)
  • ACR, American College of Rheumatology; HADS, Hospital Anxiety and Depression Scale; NPSLE, neuropsychiatric SLE; SLEDAI-2K, Systemic Lupus Erythematosus Disease Activity Index; SLICC, Systemic Lupus International Collaborating Clinics.