SLE | Controls | HR (95% CI) | Adjusted HR (95% CI) | |||
N | py | N | py | |||
Overall | 548 | 25 710 | 2450 | 280 637 | 2.42 (2.20 to 2.65) | 2.03 (1.84 to 2.23) * |
1980–1999 | 236 | 9045 | 781 | 113 450 | 3.62 (3.13 to 4.19) | 1.42 (1.20 to 1.70) † |
2000–2014 | 312 | 16 663 | 1669 | 167 157 | 1.88 (1.67 to 2.12) | 1.27 (1.11 to 1.45) † |
Males | 126 | 3471 | 642 | 42 568 | 2.37 (1.96 to 2.87) | 1.88 (1.54 to 2.29) † |
1980–1999 | 55 | 1290 | 237 | 17 324 | 2.90 (2.16 to 3.90) | 1.07 (0.76 to 1.51) † |
2000–2014 | 71 | 2180 | 405 | 24 240 | 2.02 (1.57 to 2.60) | 1.37 (1.04 to 1.81) † |
Females | 422 | 22 239 | 1808 | 238 068 | 2.48 (2.23 to 2.76) | 2.11 (1.89 to 2.35) † |
1980–1999 | 181 | 7754 | 544 | 96 126 | 3.97 (3.36 to 4.70) | 1.60 (1.30 to 1.96) † |
2000–2014 | 241 | 14 482 | 1267 | 141 917 | 1.88 (1.63 to 2.15) | 1.26 (1.08. 1.47) † |
Non-Indigenous | 494 | 24 018 | 2231 | 263 126 | 2.41 (2.18 to 2.66) | 1.99 (1.80 to 2.21) † |
1980–1999 | 213 | 8545 | 711 | 105 208 | 3.55 (3.04 to 4.13) | 1.40 (1.17 to 1.69) † |
2000–2014 | 281 | 15 470 | 1520 | 157 890 | 1.89 (1.67 to 2.15) | 1.26 (1.09 to 1.45) † |
Indigenous Australians | 54 | 1691 | 219 | 17 511 | 2.40 (1.78 to 3.23) | 3.32 (2.45 to 4.49) ‡ |
1980–1999 | 23 | 499 | 70 | 8242 | 4.65 (2.88 to 7.49) | 4.65 (2.87 to 7.52) § |
2000–2014 | 31 | 1192 | 149 | 9267 | 1.63 (1.11 to 2.40) | 2.63 (1.78 to 3.90) § |
Age groups | ||||||
<40 | 89 | 13 175 | 91 | 166 209 | 12.09 (9.02 to 16.20) | 7.46 (5.41 to 10.28) † |
40–50 | 64 | 5182 | 100 | 39 560 | 4.95 (3.62 to 6.78) | 2.83 (2.02 to 3.97) † |
50–60 | 104 | 3480 | 221 | 30 105 | 4.05 (3.21 to 5.12) | 2.57 (2.00 to 3.29) † |
60–70 | 132 | 2385 | 620 | 24 519 | 2.21 (1.83 to 2.67) | 1.82 (1.50 to 2.20) † |
≥70 | 159 | 1489 | 1418 | 20 244 | 1.49 (1.26 to 1.75) | 1.23 (1.04 to 1.46) † |
Socioeconomic status # | ||||||
Quintile 1 | 32 | 2678 | 149 | 27 223 | 2.17 (1.48 to 3.18) | 2.49 (1.67 to 3.73) † |
Quintile 2 | 28 | 2644 | 159 | 31 691 | 2.13 (1.43 to 3.19) | 1.79 (1.17 to 2.76) † |
Quintile 3 | 35 | 3451 | 186 | 38 974 | 2.14 (1.49 to 3.07) | 1.62 (1.09 to 2.42) † |
Quintile 4 | 56 | 6188 | 359 | 65 195 | 1.66 (1.25 to 2.19) | 1.60 (1.19 to 2.16) † |
Quintile 5 | 81 | 5384 | 411 | 57 002 | 2.11 (1.66 to 2.68) | 1.87 (1.46 to 2.39) † |
Since study entry | ||||||
1 year | 111 | 2035 | 454 | 20 791 | 2.48 (2.02 to 3.05) | 1.63 (1.32 to 2.02) * |
3 years | 204 | 5855 | 781 | 60 309 | 2.67 (2.29 to 3.12) | 1.85 (1.57 to 2.17) * |
5 years | 264 | 9312 | 1029 | 96 490 | 2.64 (2.31 to 3.02) | 1.96 (1.70 to 2.25) * |
Bolded HRs were statistically significant, p<0.05.
*Adjusted for age2, sex, Indigenous status, Charlson Comorbidity Index (CCI) categories, harmful alcohol consumption, obesity and smoking status.
†Adjusted for age, age2, sex, Indigenous status, CCI categories, harmful alcohol consumption, obesity and smoking status.
‡Adjusted for age2 and sex only.
§Adjusted for age, age2 and sex only.
py, person-years.