Estimated Number of New Persons Diagnosed with Systemic Lupus Erythematosus in the United States in 2018
| FEMALE | |||||
| Race/Ethnicity (Number of sites in analysis) | SLE Incidence a | Population | Estimated # SLE Cases | ||
| per 100,000 (95% CI) | Denominator | in United States (95% CI) | |||
| Race | |||||
| Black (4) | 15.9 | (12.5, 20.3) | 24,880,722 | 3,956 | (3,110, 5051) |
| White (4) | 5.7 | (4.9, 6.7) | 130,137,989 | 7,418 | (6,377, 8719) |
| Asian/PI (2) | 7.6 | (5.5, 10.4) | 12,544,896 | 953 | (6,90, 1305) |
| AI/AN (1) | 10.4 | (6.6, 14.6) | 2,238,966 | 233 | (148, 327) |
| Total b | 8.7 | (8.1,9.4) | 169,802,573 | 12,560 | (10,325 , 15,402 ) |
| Ethnicity | |||||
| Hispanic c (2) | 6.8 | (6.2, 7.6) | 30,689,083 | 2,087 | (1,903, 2332) |
| MALE | |||||
| Incidence a | Population | Estimated # SLE Cases | |||
| per 100,000 (95% CI) | Denominator | in United States (95% CI) | |||
| Race | |||||
| Black (4) | 2.4 | (1.8, 3.2) | 22,961,129 | 551 | (413, 735) |
| White (4) | 0.8 | (0.6, 1.1) | 127,942,583 | 1,024 | (768, 1,407) |
| Asian/PI (2) | 0.4 | (0.2, 0.6) | 11,660,533 | 47 | (23, 70) |
| AI/AN (1) | 3.8 | (1.6, 7.8) | 2,134,870 | 81 | (34, 167) |
| Total b | 1.2 | (0.9, 1.6) | 164,699,115 | 1,703 | (1,238 , 2,379 ) |
| Ethnicity | |||||
| Hispanic c (2) | 0.9 | (0.4, 1.9) | 31,281,605 | 282 | (125, 594) |
Systemic lupus erythematosus cases were defined according to the 1997 revised American College of Rheumatology criteria.
aEstimates for Blacks and Whites are based on pooled estimates from the four state-based registries; Asian/Pacific Islanders (Asian/PI) and Hispanics are based on pooled estimates from California and New York; American Indian/Alaska Native (AI/AN) estimates are based on the Indian Health Service Registry.
bThe pooled ‘total’ incidence estimate includes Black, White and Asian/Pacific Islanders (Asian/PI). Since the American Indian/Alaska Native (AI/AN) incidence was based on one registry and was significantly higher, it was not included in the pooled incidence per 100,000.
cHispanic ethnicity is not mutually exclusive from the race categories, i.e., all Hispanic persons are included in one of the race categories. Thus, the pooled estimates do not incorporate the Hispanic rates since that would lead to duplicate counting. Estimates for Hispanics are based on pooled estimates from California and New York.