Table 3

DLE lesion characteristics based on CLASI scores in 112 Black and 71 non-Black patients

Anatomical location and lesion characteristics	Black patients n (%)	Non-Black patients n (%)	P value*	Multivariable OR (95% CI)†‡§	P value†‡§
Erythema in any location	99 (88)	63 (89)	0.944	N/A	N/A
Scale in any location	78 (69)	53 (75)	0.464	N/A	N/A
Dyspigmentation in any location	111 (99)	56 (79)	<0.001	48.94 (5.82 to 411.77)¶	<0.001
Scarring in any location	100 (89)	55 (77)	0.030	N/A	N/A
Scalp
Erythema	75 (59)	42 (67)	0.284	N/A	N/A
Scale/hypertrophy	58 (52)	34 (48)	0.607	N/A	N/A
Dyspigmentation	92 (82)	32 (48)	<0.001	5.85 (2.94 to 11.61)**	<0.001
Scarring alopecia	89 (79)	40 (56)	0.001	3.00 (1.56 to 5.78)††	0.001
Non-scarring alopecia	49 (44)	29 (41)	0.699	N/A	N/A
Ears
Erythema	36 (32)	20 (28)	0.570	N/A	N/A
Scale/hypertrophy	34 (30)	22 (31)	0.928	N/A	N/A
Dyspigmentation	63 (56)	25 (35)	0.006	2.89 (1.50 to 5.54)‡‡	0.001
Scarring	31 (28)	14 (20)	0.223	N/A	N/A

*P value was calculated with χ² test.
†Blank values represented by ‘–’ indicate variables for which race was not a significant factor in the multivariable analyses.
‡N/A represents values for which multivariable analyses were not performed.
§Predictor variables (race, age at initial visit, gender, disease duration at initial visit, follow-up duration, smoking status, presence of SLE) were included in multivariable analyses.
¶Race and age at initial visit (OR=0.92, 95% CI 0.88 to 0.97, p=0.002) were significant predictors of dyspigmentation in any anatomical location.
**Race and follow-up duration (OR=1.17, 95% CI 1.01 to 1.36, p=0.04) were significant predictors of scalp dyspigmentation.
††Race was the only significant predictor of scarring alopecia.
‡‡Race and age at initial visit (OR=0.96, 95% CI 0.94 to 0.98, p=0.001) were also significant predictors of ear dyspigmentation.
CI, confidence interval; CLASI, Cutaneous Lupus Erythematosus Disease Area and Severity Index; DLE, discoid lupus erythematous; N/A, not available; OR, odds ratio.