DLE lesion distribution based on CLASI scores in 112 Black and 71 non-Black patients
| Anatomical location | Black patients n (%) | Non-Black patients n (%) | Univariate OR (95% CI) | P value* | Multivariable OR (95% CI)†‡ | P value†‡ |
| Scalp | 97 (87) | 51 (72) | 2.54 (1.12 to 5.79) | 0.013 | 2.54 (1.20 to 5.37) | 0.015 |
| Ears | 66 (59) | 32 (45) | 0.92 (0.92 to 3.33) | 0.067 | 1.97 (1.06 to 3.68)§ | 0.032 |
| Nose/malar area | 60 (59) | 40 (56) | 0.89 (0.47 to 1.70) | 0.714 | – | – |
| Rest of face | 63 (56) | 37 (53) | 1.18 (0.62 to 2.24) | 0.584 | – | – |
| V area of neck (front) | 22 (20) | 19 (27) | 0.67 (0.31 to 1.44) | 0.260 | – | – |
| Posterior neck/shoulders | 22 (20) | 20 (28) | 0.62 (0.29 to 1.33) | 0.181 | – | – |
| Chest | 20 (18) | 18 (25) | 0.64 (0.29 to 1.41) | 0.223 | – | – |
| Abdomen | 10 (9) | 1 (1) | N/A¶ | 0.053** | – | – |
| Back and buttocks | 27 (24) | 18 (25) | 0.94 (0.44 to 1.99) | 0.849 | – | – |
| Arms | 40 (36) | 25 (35) | 1.02 (0.53 to 2.00) | 0.945 | – | – |
| Hands | 19 (17) | 9 (13) | 1.41 (0.56 to 3.77) | 0.432 | – | – |
| Legs | 23 (21) | 18 (25) | 0.76 (0.36 to 1.65) | 0.446 | – | – |
| Feet | 20 (18) | 8 (11) | 1.71 (0.67 to 4.77) | 0.228 | – | – |
| Mucous membrane | 15 (13) | 9 (13) | 1.07 (0.41 to 2.94) | 0.889 | – | – |
*P value was calculated with χ2 test unless otherwise specified.
†'–’ indicates that race was not a significant factor in multivariable analyses.
‡Predictor variables (race, age at initial visit, gender, disease duration at initial visit, follow-up duration, smoking status, presence of SLE) were included in multivariable analyses.
§Race was the only significant predictor variable for scalp involvement. Race and age at initial visit (OR=0.97, 95% CI 0.95 to 0.99, p=0.015) were significant predictor variables for ear involvement.
¶OR not calculated due to a low number of patients with abdomen involvement in the non-black patient group.
**P value was calculated with Fisher’s exact test.
CI, confidence interval; CLASI, Cutaneous Lupus Erythematosus Disease Area and Severity Index; DLE, discoid lupus erythematous; N/A, not available; OR, odds ratio.