Table 1

Estimated number of new persons diagnosed with SLE in the USA in 2018

Female
Race/ethnicity (number of sites in the analysis)SLE incidence* per 100 000 (95% CI)Population denominatorEstimated SLE cases in the USA, n (95% CI)
Race
Black (4)15.9 (12.5 to 20.3)24 880 7223956 (3110 to 5051)
White (4)5.7 (4.9 to 6.7)130 137 9897418 (6377 to 8719)
Asian/PI (2)7.6 (5.5 to 10.4)12 544 896953 (690 to 1305)
AI/AN (1)10.4 (6.6 to 14.6)2 238 966233 (148 to 327)
Total†8.7 (8.1 to9.4)169 802 57312 560 (10 325 to 15 402)
Ethnicity
Hispanic‡ (2)6.8 (6.2 to 7.6)30 689 0832087 (1903 to 2332)
Male
Incidence* per
100 000 (95% CI)
Population denominatorEstimated SLE cases in the USA, n (95% CI)
Race
Black (4)2.4 (1.8 to 3.0)22 961 129551 (413 to 689)
White (4)0.8 (0.6 to 1.1)127 942 5831024 (768 to 1407)
Asian/PI (2)0.4 (0.2 to 0.6)11 660 53347 (23 to 70)
AI/AN (1)3.8 (1.6 to 7.8)2 134 87081 (34 to 167)
Total†1.2 (0.9 to 1.6)164 699 1151703 (1238 to 2333)
Ethnicity
Hispanic‡ (2)0.9 (0.4 to 1.9)31 281 605282 (125 to 594)
  • SLE cases were defined according to the 1997 revised American College of Rheumatology criteria.

  • *Estimates for black and white persons are based on pooled estimates from the four state-based registries; Asian/PI and Hispanics are based on pooled estimates from California and New York; AI/AN estimates are based on the Indian Health Service registry.

  • †The pooled ‘total’ incidence estimate includes black, white and Asian/PI. Since the AI/AN incidence was based on one registry and was significantly higher, it was not included in the pooled incidence per 100 000.

  • ‡Hispanic ethnicity is not mutually exclusive from the race categories, that is, all Hispanic persons are included in one of the race categories. Thus, the pooled estimates do not incorporate the Hispanic rates since that would lead to duplicate counting. Estimates for Hispanics are based on pooled estimates from California and New York.

  • AI/AN, American Indian/Alaska Native; Asian/PI, Asian/Pacific Islander.