Outcome | Number of studies | Follow-up duration | GC, number | PDN, daily dose, mg | PDN, cumulative dose, g | Par. GC (methylprednisolone), number |
SDI differences | 29 | 29 | 24 | 10 | 16 | 3 |
Cataracts | 17 | 17 | 14 | 5 | 10 | 3 |
CVA | 15 | 15 | 12 | 2 | 4 | 3 |
MI | 16 | 16 | 13 | 4 | 6 | 3 |
Overall CVE | 18 | 18 | 17 | 6 | 9 | 3 |
Osteonecrosis | 22 | 22 | 17 | 8 | 12 | 8 |
Osteoporosis and fractures | 16 | 16 | 12 | 5 | 11 | 3 |
CVA, cerebrovascular accident; CVE, cardiovascular event; GC, glucocorticoids; MI, myocardial infarction; Par, parenteral; PDN, prednisone; SDI, SLICC Damage Index.