Estimated overall rates of observed damage
| Outcome | Number of studies included | Rate* (95% CI) | I2 (Percentage) | τ2 |
| Changes in SDI scores | 29 | 9.89 (7.59 to 12.88) | 99.2 | 0.50 |
| Cataracts | 17 | 0.95 (0.65 to 1.40) | 91.5 | 0.51 |
| CVA | 15 | 0.53 (0.38 to 0.73) | 85.1 | 0.30 |
| MI | 16 | 0.40 (0.27 to 0.59) | 80.1 | 0.41 |
| Overall CVE | 18 | 1.09 (0.75 to 1.59) | 92.5 | 0.55 |
| Osteonecrosis | 22 | 1.14 (0.82 to 1.60) | 92.0 | 0.51 |
| Osteoporosis and fractures | 16 | 0.78 (0.50 to 1.22) | 92.1 | 0.64 |
*Rate is patients developing damage per 100 patient years except for change in SDI which is rate of SDI change per 100 patient years.
CVA, cerebrovascular accident; CVE, cardiovascular events; I2, heterogeneity; MI, myocardial infarction; SDI, SLICC Damage Index; τ2, absolute heterogeneity.