Comparison of sensitivity, specificity, PPV and NPV between risk calculators
| Sensitivity % (95% CI) | Specificity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) | |
| QRISK3 >10% | 45.3 (32.8 to 58.2) | 79.5 (74.5 to 83.9) | 32.2 (25.1 to 40.3) | 87.1 (84.3 to 89.5) |
| QRISK3 >20% | 21.4 (12.5 to 32.9) | 94.6 (91.5 to 96.9) | 48.4 (32.8 to 64.8) | 83.8 (82.0 to 85.4) |
| ASCVD >10% | 12.2 (4.1 to 26.2) | 94.0 (88.1 to 97.6) | 41.7 (19.4 to 68.0) | 75.3 (72.9 to 77.5) |
| FRS >10% | 10.9 (4.5 to 21.3) | 92.8 (89.1 to 95.5) | 25.0 (12.9 to 42.9) | 82.5 (81.2 to 83.8) |
| Modified FRS >10% | 40.6 (28.5 to 53.6) | 72.1 (66.5 to 77.2) | 24.3 (18.5 to 13.3) | 84.6 (81.6 to 87.2) |
| High-risk PREDICTS | 73.4 (60.9 to 83.3) | 65.2 (59.6 to 70.6) | 30.9 (26.6 to 35.7) | 92.1 (88.4 to 94.6) |
ASCVD, Atherosclerotic Cardiovascular Disease; FRS, Framingham Risk Score; NPV, negative predictive value; PPV, positive predictive value; PREDICTS, Predictors of Risk for Elevated Flares, Damage Progression and Increased Cardiovascular Disease in Patients with SLE.