Maternal and neonatal clinical outcomes and assessment of cardiac function of 10 pregnant patients with SLE-PAH within 6 months after delivery
| Case number | Maternal clinical outcomes | Neonatal clinical outcomes | Assessment of cardiac function | |||||||||||||
| Week of completed pregnancies (gestational age, weeks) | Mode of delivery | Anaesthesia | Maternal status (compared with baseline) | Neonatal status | Birth weight (g) | 5 min Apgar score | NICU stay duration (days) | Severe diseases | WHO functional class | Echocardiography | NT-proBNP (pg/mL) | |||||
| PASP (mm Hg) | RVTD (mm) | EF (%) | TAPSE (mm) | Pericardial effusion | ||||||||||||
| 1 | 24+0 | Induced labour | Epidural | Improved | NA | II | 56 | NR | NR | NR | NR | 32 | ||||
| 2 | 15+6 | Induced labour | General | Improved | NA | II | 34 | 34 | 63 | 21 | No | 170 | ||||
| 3 | 35+4 | Caesarean | Epidural | Stable | Alive | 2820 | 10 | 5 | No | I | 86 | 41 | 67 | 15 | No | 127 |
| 4 | 31+0 | Vaginal | Epidural | Improved | Alive | 1700 | 10 | 10 | No | IV | 83 | 50 | 71 | 15 | Trace | 4003 |
| 5 | 38+2 | Caesarean | Epidural | Stable | Alive | 3000 | 10 | 0 | No | II | 49 | 44 | 35 | NR | No | 238 |
| 6 | 20+4 | Induced labour | General | Death | NA | IV | NA | NA | NA | NA | NA | 26 988 | ||||
| 7 | 25+5 | Induced labour | General | Improved | NA | II | 59 | 32 | 71 | 20 | No | 66 | ||||
| 8 | 31+5 | Caesarean | Epidural | Improved | Alive | 1500 | 10 | 20 | No | II | 23 | NR | 48 | NR | No | 186 |
| 9 | 31+2 | Caesarean | Epidural | Improved | Alive | 1400 | 8 | 30 | No | II | 84 | 39 | 78 | 14 | No | 184 |
| 10 | 36+5 | Caesarean | General | Improved | Alive | <2500 (no exact data) | 10 | 4 | No | II | 78 | 44 | 68 | 15 | No | 316 |
Echocardiography: PASP (pulmonary arterial systolic pressure).
EF, ejection fraction; NA, not applicable; NICU, neonatal intensive care unit; NR, not reported; NT-proBNP, N-terminal pro-brain natriuretic peptide; PAH, pulmonary arterial hypertension; PASP, pulmonary arterial systolic pressure; RVTD, right ventricular transverse diameter; SLE, systemic lupus erythematosus; TAPSE, tricuspid annular plane systolic excursion.