Literature review of cases of pregnancy in patients with SLE-PAH
| Article | Clinical characteristics and outcomes | Assessment of cardiac function | ||||||||
| Age | Planned pregnancy under awareness of risk | Week of completed pregnancies (gestational age, weeks) | Mode of delivery | Anaesthesia | Maternal outcomes (cause of death, if applicable) | Neonatal status | WHO functional class (baseline, outcome, if outcome available) | mPAP (mm Hg) (baseline, outcome, if outcome available) | Baseline NT-proBNP (pg/mL) | |
| Zhou et al24 | 19 | No | NR | NR | NR | Death (heart failure, PAH crisis) | Death | IV | NR (RHC confirmed) | NR |
| Lim et al25 | 33 | No | 40+6 | Vaginal | Epidural | Alive | Alive | (II, II) | 42.8 | 1241 |
| 38 | No | 36+4 | Vaginal | Epidural | Alive | Alive | (II, II) | 34.1 | 79 | |
| Meng et al26 | NR | No | 34 | Vaginal | Epidural | Alive | Alive | II | NR (25–50) | NR |
| NR | Yes | 29 | Caesarean | Spinal | Alive | Alive | IV | NR (≥50) | NR | |
| NR | Yes | 32 | Caesarean | Epidural | Alive | Alive | IV | NR (≥50) | NR | |
| Corbach et al27 | 28 | No | 37+1 | Caesarean | Spinal | Alive | Alive | (III, III) | NR (RHC confirmed) | 70 |
| Goland et al13 | 30 | No | 36+3 | Caesarean | NR | Alive | Alive | (II, II) | 51.7 | NR |
| McMillan et al28 | 30 | No | 31 | Caesarean | General | Death (acute postpartum cor pulmonale, small vessel lung disease) | Alive | NR | 70–80 | NR |
| Tabarsi et al14 | 39 | No | 36 | Caesarean | Epidural | Alive | Alive | (III, II) | NR (PASP 83) | NR |
| Streit et al15 | 29 | Yes | 37 | Caesarean | Epidural | Alive | Alive | (III, IV) | (35, 21) | 70 |
| Kawabe et al16 | 31 | Yes | 28+1 | Caesarean | General | Alive | Alive | (I, I) | (34, 34) | NR |
| Mirdamadi et al17 | 30 | No | 36 | Caesarean | General | Alive | Alive | NR | (47, 110) | NR |
| Smith et al18 | 24 | Yes | 28+1 | Caesarean | General | Alive | Alive | NR | 49 | NR |
mPAP, mean pulmonary artery pressure; NR, not reported; NT-proBNP, N-terminal pro-brain natriuretic peptide; PAH, pulmonary arterial hypertension; PASP, pulmonary arterial systolic pressure; RHC, right heart catheterisation; SLE, systemic lupus erythematosus.