Pregnancy outcomes
| All (N=216) n (%) | No low-dose acetylsalicylic acid (n=134) n (%) | Low-dose acetylsalicylic acid (n=82) n (%) | P value* | |
| Gestational diabetes | 3 (2.1) | 1 (1.3) | 2 (3.0) | 0.60 |
| Pre-eclampsia | 13 (6.1) | 11 (8.3) | 2 (2.4) | 0.14 |
| Early-onset pre-eclampsia (<34 weeks) | 7 (3.2) | 6 (4.4) | 1 (1.2) | 0.90 |
| Intrauterine fetal death | 3 (1.4) | 3 (2.2) | 0 (0.0) | 0.29 |
| Intrauterine growth restriction | 12 (5.6) | 7 (5.3) | 5 (6.2) | 0.77 |
| Gestational weeks at delivery† | 39 (37–40) | 39 (37–40) | 39 (37–39) | 0.55 |
| Preterm delivery | 40 (18.9) | 23 (17.7) | 17 (20.7) | 0.59 |
| Birth weight <2500 g | 33 (15.6) | 19 (14.4) | 14 (17.5) | 0.56 |
| Birth weight <1500 g | 13 (6.1) | 11 (8.3) | 2 (2.5) | 0.14 |
| Size for gestational age | 0.09 | |||
| Small | 23 (11.0) | 10 (7.7) | 13 (16.5) | |
| Appropriate | 182 (87.1) | 118 (90.8) | 64 (81.0) | |
| Large | 4 (1.9) | 2 (1.5) | 2 (2.5) | |
| Composite outcome‡ | 65 (30.1) | 38 (28.4) | 27 (32.9) | 0.54 |
Number of missing data: gestational diabetes: 74; pre-eclampsia: 2; intrauterine fetal death: 0; intrauterine growth restriction: 2; gestational week: 6; preterm delivery: 4; birth weight: 8; birth weight <2500 g: 4; birth weight <1500 g: 3; size for gestational age: 7.
*P values from Fisher’s exact test for categorical variables and Kruskal-Wallis test for continuous variables.
†Median (IQR).
‡Composite outcome: at least one of pre-eclampsia, intrauterine fetal death, intrauterine growth restriction, preterm delivery, birth weight <2500 g and small for gestational age.