Table 3

Logistic regression models for the association of serological variables with cognitive impairment in patients with SLE

Laboratory variable	OR (95% CI)	P value
Anti-dsDNA	0.92 (0.36 to 2.37)	0.87
Anti-chromatin	0.63 (0.24 to 1.68)	0.36
Anti-ribosomal P	N/A	N/A
Anti-Ro (60, 52)	0.878 (0.33 to 2.33)	0.79
Anti-La	1.10 (0.28 to 4.37)	0.89
Anti-Sm	0.74 (0.21 to 2.63)	0.64
Anti-RNP (A, 68)	0.61 (0.21 to 1.73)	0.35
Anticardiolipin	1.16 (0.33 to 4.10)	0.81
Anti-β2 glycoprotein I	1.66 (0.36 to 7.77)	0.52
LAC	2.11 (0.69 to 6.39)	0.19
Anticardiolipin or anti-β2 glycoprotein I or LAC	1.62 (0.59 to 4.45)	0.35
Anti-NR2 (peptide mix)	1.23 (0.32 to 4.67)	0.77
Anti-NR2 (protein mix)	0.55 (0.13 to 2.32)	0.42
Anti-GFAP	1.73 (0.57 to 5.29)	0.34
Anti-MPP1	0.45 (0.16 to 1.22)	0.12
Low C3	4.37 (1.34 to 14.23)	0.06
Low C4	1.13 (0.41 to 3.14)	0.81
Elevated neurofilament light chains	1.20 (0.41 to 3.51)	0.74

	NR2 protein mix MFI	NR2 peptide mix MFI	MPP1 MFI	GFAP MFI
Positive	≥1000	≥1000	≥1000	≥1000

dsDNA, double-stranded DNA; GFAP, glial fibrillar acidic protein; LAC, lupus anticoagulant; MFI, median fluorescence intensity; MPP1, M-phase phosphoprotein 1; N/A, not available due insufficient data for model; NR2, N-methyl-D-aspartic acid receptor 2; RNP, ribonucleoprotein.