Table 2

Comparison of clinical characteristics between 13 new-onset SLE patients before and after treatment

BaselineAfter treatmentP value
24-hour urine protein in LN, mg, median (IQR)*1083.00 (561.50,1701.50)177.00 (146.00,224.50)<0.0001
ANA, U/mL, median (IQR)*417.30 (374.20,466.00)342.15 (213.30,372.40)0.019
Anti-dsDNA, IU/mL, mean±SD†329.07±208.06177.92±110.120.001
Complement 3, g/L, mean±SD†0.53±0.170.82±0.18<0.001
Low complement 3, n (%)‡12 (92.31)4 (30.77)0.004
Disease activity (SLEDAI-2K, median (IQR))*10.00 (9.00,12.50)4.00 (1.25,4.75)<0.0001
 SLEDAI-2K<4, n (%)010 (76.92)
 SLEDAI-2K 4–9, n (%)3 (23.08)3 (23.08)
 SLEDAI-2K 10–14, n (%)8 (61.54)0
 SLEDAI-2K≥15, n (%)2 (15.38)0
  • *Non-normally distributed variables were compared using the Mann-Whitney U tests.

  • †Normally distributed continuous variables were compared using Student’s t-tests.

  • ‡Categorical variables were compared using the χ2 tests and Fisher’s exact tests.