All | Intermittent | Persistent | |
n=42 | n=18 | n=24 | |
ANA+ | 40 (95%)*† | 18 (100%) | 22 (92%)*† |
Immunology | 32 (77%) | 16 (89%) | 16 (67%) |
Anti-dsDNA antibody OR anti-Smith antibody | 28 (67%) | 14 (78%) | 14 (58%) |
Anti-cardiolipin antibodies OR anti-B2GP1 antibodies or lupus anticoagulant | 8 (19%) | 5 (28%) | 3 (13%) |
Low C3 and low C4 | 15 (36%) | 8 (44%) | 7 (29%) |
Low C3 or low C4 | 9 (21%) | 6 (33%) | 3 (13%) |
Muskuloskeletal | |||
Arthritis/joint involvement | 34 (81%) | 15 (83%) | 19 (79%) |
Mucocutaneous | 39 (93%) | 17 (94%) | 22 (92%) |
Acute cutaneous lupus | 33 (79%) | 16 (89%) | 17 (71%) |
Oral ulcers | 23 (55%) | 10 (56%) | 13 (54%) |
Non-scarring alopecia | 22 (52%) | 8 (44%) | 14 (58%) |
Subacute cutaneous or discoid lupus | 11 (26%) | 6 (33%) | 5 (21%) |
Renal | 15 (36%) | 10 (56%) | 5 (21%) |
Renal biopsy class II, III, IV or V | 10 (24%) | 8 (44%) | 2 (8%) |
Proteinuria >0.5 g/24 hours (no biopsy) | 5 (12%) | 2 (11%) | 3 (13%) |
Serosal | 8 (19%) | 5 (28%) | 3 (13%) |
Pleural or pericardial effusion | 5 (12%) | 3 (17%) | 2 (8%) |
Acute pericarditis | 5 (12%) | 2 (11%) | 3 (13%) |
Haematological | 24 (57%) | 13 (72%) | 11 (46%) |
Leucopenia | 21 (50%) | 10 (56%) | 11 (46%) |
Thrombocytopenia | 4 (10%) | 3 (17%) | 1 (4%) |
Autoimmune haemolysis | 2 (5%) | 2 (11%) | 0 (0%) |
Constitutional | |||
Fever | 4 (10%) | 2 (11%) | 2 (8%) |
Neurological | 2 (5%) | 1 (6%) | 1 (4%) |
Delirium | 1 (2%) | 1 (6%) | 0 (0%) |
Seizure | 1 (2%) | 0 (0%) | 1 (4%) |
Psychosis | 0 (0%) | 0 (0%) | 0 (0%) |
EULAR/ACR criteria met | 37 (88%) | 18 (100%) | 19 (79%) |
1997 ACR criteria met‡ | 40 (95%) | 18 (100%) | 22 (92%) |
SLICC criteria met‡ | 40 (95%) | 18 (100%) | 22 (92%) |
*One participant is ANA− but dsDNA+.
†One participant ANA 1:40.
‡n=2 participants met 1997 ACR criteria but not SLICC criteria and n=2 participants met SLICC criteria but not 1997 ACR criteria.
ACR, American College of Rheumatology; EULAR, European Alliance of Associations for Rheumatology; SLICC, Systemic Lupus International Collaborating Clinics.