Table 3

2019 EULAR/ACR criteria

AllIntermittentPersistent
n=42n=18n=24
ANA+40 (95%)*†18 (100%)22 (92%)*†
Immunology32 (77%)16 (89%)16 (67%)
Anti-dsDNA antibody OR anti-Smith antibody28 (67%)14 (78%)14 (58%)
Anti-cardiolipin antibodies OR anti-B2GP1 antibodies or lupus anticoagulant8 (19%)5 (28%)3 (13%)
Low C3 and low C415 (36%)8 (44%)7 (29%)
Low C3 or low C49 (21%)6 (33%)3 (13%)
Muskuloskeletal
Arthritis/joint involvement34 (81%)15 (83%)19 (79%)
Mucocutaneous39 (93%)17 (94%)22 (92%)
Acute cutaneous lupus33 (79%)16 (89%)17 (71%)
Oral ulcers23 (55%)10 (56%)13 (54%)
Non-scarring alopecia22 (52%)8 (44%)14 (58%)
Subacute cutaneous or discoid lupus11 (26%)6 (33%)5 (21%)
Renal15 (36%)10 (56%)5 (21%)
Renal biopsy class II, III, IV or V10 (24%)8 (44%)2 (8%)
Proteinuria >0.5 g/24 hours (no biopsy)5 (12%)2 (11%)3 (13%)
Serosal8 (19%)5 (28%)3 (13%)
Pleural or pericardial effusion5 (12%)3 (17%)2 (8%)
Acute pericarditis5 (12%)2 (11%)3 (13%)
Haematological24 (57%)13 (72%)11 (46%)
Leucopenia21 (50%)10 (56%)11 (46%)
Thrombocytopenia4 (10%)3 (17%)1 (4%)
Autoimmune haemolysis2 (5%)2 (11%)0 (0%)
Constitutional
Fever4 (10%)2 (11%)2 (8%)
Neurological2 (5%)1 (6%)1 (4%)
Delirium1 (2%)1 (6%)0 (0%)
Seizure1 (2%)0 (0%)1 (4%)
Psychosis0 (0%)0 (0%)0 (0%)
EULAR/ACR criteria met37 (88%)18 (100%)19 (79%)
1997 ACR criteria met‡40 (95%)18 (100%)22 (92%)
SLICC criteria met‡40 (95%)18 (100%)22 (92%)
  • *One participant is ANA− but dsDNA+.

  • †One participant ANA 1:40.

  • ‡n=2 participants met 1997 ACR criteria but not SLICC criteria and n=2 participants met SLICC criteria but not 1997 ACR criteria.

  • ACR, American College of Rheumatology; EULAR, European Alliance of Associations for Rheumatology; SLICC, Systemic Lupus International Collaborating Clinics.