Sex (male/female) | 2/8 | |
Age (years) | 38.6 (21–68) | |
Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) score | 12 (8–24) | |
Anti-dsDNA antibodies (kU/L) | 327 (42–1286) | <100 |
C3 (g/L) | 0.65 (0.42–1.9) | 0.9–1.8 |
C4 (g/L) | 0.08 (0.07–0.3) | 0.1–0.4 |
Treatment (number of patients) | | |
Hydroxychloroquine | 8 | |
Prednisolone | 5 | |
Azathioprine | 2 | |
Organ involvement | | |
Fever (>38.3°C) | 1 | |
Delirium | 0 | |
Psychosis | 1 | |
Seizure | 0 | |
Non-scarring alopecia | 3 | |
Oral ulcers | 2 | |
Subacute cutaneous or discoid lupus | 7 | |
Acute cutaneous lupus | 2 | |
Pleural or pericardial effusion | 2 | |
Acute pericarditis | 0 | |
Joint involvement | 5 | |
Proteinuria (>0.5 g/24 hours) | 2 | |
Lupus nephritis | 1 | |
Laboratory parameter | | |
ANA ≥1:80 | 10 | |
Leucopenia (<4.000 /mm3) | 3 | |
Thrombocytopenia (<100.000 /mm3) | 2 | |
Autoimmune haemolysis | 0 | |
Antiphospholipid antibodies | 3 | |
Low C3 or low C4 | 6 | |
Low C3 and low C4 | 3 | |
Anti-dsDNA or anti-Sm antibodies | 10 | |
Characteristics of healthy controls (n=9) | | |
Sex (male/female) | 2/9 | |
Age (years) | 31.6 (24–62) | |