Table 3

GFR and serum creatinine levels during follow-up period by mPERR status

Number of years post biopsy
1 year2 years3 years4 years5 years
N (%)N (%)N (%)N (%)N (%)
GFR
Responders*114 (67.1)105 (67.3)86 (68.3)71 (68.3)64 (70.3)
<60 mL/min/1.73 m24 (3.5)7 (6.7)6 (7.0)5 (7.0)5 (7.8)
≥60 mL/min/1.73 m2110 (96.5)98 (93.3)80 (93.0)66 (93.0)59 (92.2)
Non-responders*56 (32.9)51 (32.7)40 (31.7)33 (31.7)27 (29.7)
<60 mL/min/1.73 m224 (42.9)20 (39.2)15 (37.5)10 (30.3)7 (25.9)
≥60 mL/min/1.73 m232 (57.1)31 (60.8)25 (62.5)23 (69.7)20 (74.1)
Serum creatinine
Responders*114 (67.1)105 (67.3)86 (68.3)71 (68.3)64 (70.3)
<1.0 mg/dL88 (77.2)81 (77.1)56 (65.1)45 (63.4)41 (64.1)
≥1.0 mg/dL26 (22.8)24 (22.9)30 (34.9)26 (36.6)23 (35.9)
Non-responders*56 (32.9)51 (32.7)40 (31.7)33 (31.7)27 (29.7)
<1.0 mg/dL22 (39.3)22 (43.1)22 (55.0)18 (54.6)14 (51.9)
≥1.0 mg/dL34 (60.7)29 (56.9)18 (45.0)15 (45.5)13 (48.2)
  • *Denominator for percentage is the total number of patients with available laboratory results for each respective year.

  • GFR, glomerular filtration rate; mPERR, modified primary efficacy renal response.