Classification performance of the different cut-off points for EULAR/ACR criteria (≥8, ≥9, ≥10, ≥11, ≥12, ≥13, ≥14 and ≥15) in the SLE and control cohorts
| Threshold | ||||||||
| 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | |
| Sensitivity | 98.6% | 98.3% | 97.4% | 96.6% | 95.2% | 92.0% | 89.5% | 86.9% |
| Specificity | 82.9% | 85.2% | 91.4% | 93.2% | 94.8% | 95.8% | 97.7% | 98.2% |
| Accuracy | 90.4% | 91.5% | 94.3% | 94.8% | 95.0% | 94.0% | 93.8% | 92.8% |
| PPV | 84.0% | 85.9% | 91.2% | 92.9% | 94.4% | 95.3% | 97.2% | 97.8% |
| NPV | 98.5% | 98.2% | 97.5% | 96.8% | 95.5% | 92.9% | 91.0% | 89.2% |
| +LR | 5.766 | 6.642 | 11.326 | 14.206 | 18.308 | 21.905 | 38.913 | 48.278 |
| −LR | 0.017 | 0.020 | 0.028 | 0.036 | 0.051 | 0.084 | 0.107 | 0.133 |
ACR, American College of Rheumatology; EULAR, European Alliance of Associations for Rheumatology; −LR, negative likelihood ratio; +LR, positive likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.