Clinical characteristics n=25 subjects | n (%) or median (range) |
Age (years) | 15 (9–17) |
Female | 21 (84) |
Race | |
White | 6 (24) |
Black | 2 (8) |
Asian | 2 (8) |
Other | 14 (56) |
Unknown | 1 (4) |
Ethnicity | |
Hispanic | 9 (36) |
Not Hispanic | 13 (52) |
Unknown | 3 (12) |
Weight (kg) | 66 (39–118) |
Body mass index (kg/m2) % of the 95th percentile | 91 (9–184) |
HCQ total daily dose (mg), per patient | 300 (87.5–400) |
CYP2D6 phenotype (genotype) | |
Normal (*1/*1, *1/*17, *1/*41, *1/*9) | 13 (52) |
Intermediate (*1/*4, *1/*5, *5/*10) | 9 (36) |
Poor (*4/*5) | 1 (4) |
Missing | 2 (8) |
HCQ, hydroxychloroquine.