Patient demographics by SLE Pregnancy Cohort
| Development | External validation data sets | |||
|---|---|---|---|---|
| PROMISSE | Bronx, NY | NYC, NY | Pisa, Italy | |
| n=385, 71 APOs | n=96, 23 APOs | n=62, 16 APOs | n=152, 28 APOs | |
| event rate=18.4% | event rate = 24.0% | event rate = 25.8% | event rate=18.4% | |
| Maternal age , years | 31 (28,34) | 29 (24,34) | 33 (29,33.5) | 32 (28,36) |
| Non-Hispanic White (%) | 49.3 | 0.0 | 27.4 | 98.7 |
| Platelet count, x 109 cells/L | 243 (204,296) | 235 (209,259) | 228 (188,274) | 204 (188, 238) |
| Diastolic BP, mmHg | 67 (60,73) | 72.5 (63,79) | 70 (64,75) | 70 (61,75) |
| LAC + (%) | 8.1 | 19.1 | 22.6 | 15.9 |
| PGA > 1 (%) | 10.6 | 4.4 | 11.1 | 7.9 |
| SLE disease activity score | 2 (0,4) | 1.5 (0,2) | 2 (0,5) | 2 (0,4) |
| Low C3 (%) | 20.2 | 27.6 | 24.2 | 52.6 |
| aCL IgG + (%) | 6.1 | 2.1 | 9.7 | 11.8 |
| aCL IgM + (%) | 1.8 | 0.0 | 16.1 | 1.3 |
| Current glucocorticoid use (%) | 39.7 | 50.5 | 23.1 | 58.9 |
| Current anti hypertensives use (%) | 8.6 | 12.6 | 4.8 | 5.3 |
| Current hydroxychloroquine use (%) | 64.7 | 54.3 | 84.6 | 63.4 |
Data are summarized as median (IQR), unless otherwise indicated; BP=blood pressure