Abstract 607 Table 1

PHQ-8 summary

All patientsExcluding patients taking antidepressants
Anifrolumab 300 mg N=360Placebo N=365Anifrolumab 300 mg N=360Placebo N=365
n MeanaSD Changebn MeanaSD Changebn MeanaSD Changebn MeanaSD Changeb
Baseline 341 9.7 6.26 348 9.7 6.11 335 9.5 6.21 338 9.7 6.09
Week 24 295 7.6 5.89 –2.1 303 8.0 6.00 –1.5 289 7.5 5.84 –2.1 293 8.1 6.00 –1.5
Week 52 266 7.8 5.99 –2.0 261 7.9 6.03 –1.3 262 7.7 6.00 –2.0 252 7.9 5.96 –1.2
  • SD, standard deviation.

  • aPHQ-8 classifications: 0–4 = none, 5–9 = mild, 10–14 = moderate, 15–19 = moderately severe, and 20–24 = severe.

  • bMean change from baseline.