Table 4

Immunosuppressive treatment regimens in 95 NPSLE patients with 101 NPSLE events

Neuropsychiatric events for which immunosuppressive therapy was initiated
(n=101)
Treatment regimen
 Induction24 (24)
 Induction and maintenance74 (73)
 General3 (3)
Type of medication
 Methylprednisolone54 (53)
 Prednisone98 (97)
 Cyclophosphamide43 (42)
  NIH, 6x29 (67)
  NIH, complete (12x)10 (23)
  Euro-Lupus4 (10)
 Azathioprine49 (49)
 Mycophenolate mofetil12 (12)
 Biological3 (3)
  Rituximab2 (2)
  Belimumab1 (1)
 Other4 (4)
  IVIG2 (2)
  Methotrexate1 (1)
  Ciclosporin1 (1)
Concomitant treatment*
 Hydroxychloroquine66 (65)
 Antiplatelet54 (53)
 Anticoagulant18 (18)
  • Results are presented as n (%).

  • *Treatment already present at time of presentation with NP symptoms or started for ischaemic manifestations.

  • IVIG, intravenous immune globulin; NIH, National Institute of Health; NP, neuropsychiatric; NPSLE, neuropsychiatric SLE.