Immunosuppressive treatment regimens in 95 NPSLE patients with 101 NPSLE events
Neuropsychiatric events for which immunosuppressive therapy was initiated (n=101) | |
Treatment regimen | |
Induction | 24 (24) |
Induction and maintenance | 74 (73) |
General | 3 (3) |
Type of medication | |
Methylprednisolone | 54 (53) |
Prednisone | 98 (97) |
Cyclophosphamide | 43 (42) |
NIH, 6x | 29 (67) |
NIH, complete (12x) | 10 (23) |
Euro-Lupus | 4 (10) |
Azathioprine | 49 (49) |
Mycophenolate mofetil | 12 (12) |
Biological | 3 (3) |
Rituximab | 2 (2) |
Belimumab | 1 (1) |
Other | 4 (4) |
IVIG | 2 (2) |
Methotrexate | 1 (1) |
Ciclosporin | 1 (1) |
Concomitant treatment* | |
Hydroxychloroquine | 66 (65) |
Antiplatelet | 54 (53) |
Anticoagulant | 18 (18) |
Results are presented as n (%).
*Treatment already present at time of presentation with NP symptoms or started for ischaemic manifestations.
IVIG, intravenous immune globulin; NIH, National Institute of Health; NP, neuropsychiatric; NPSLE, neuropsychiatric SLE.