NPSLE manifestations (n=195) in 95 patients with 101 events for which immunosuppressive treatment was initiated
Neuropsychiatric events for which immunosuppressive therapy was initiated (n=101) | |
NPSLE phenotype | |
Inflammatory | 70 (70) |
Combined (inflammatory+ischaemic) | 31 (30) |
1999 ACR NPSLE syndromes | |
Aseptic meningitis | 1 (1) |
Cerebrovascular disease | 31 (30) |
Demyelinating syndrome | 0 (0) |
Headache | 11 (11) |
Movement disorder (chorea) | 4 (4) |
Myelopathy | 11 (11) |
Seizure disorders | 8 (8) |
Acute confusional state | 10 (10) |
Anxiety disorder | 2 (2) |
Cognitive dysfunction | 50 (50) |
Mood disorder | 15 (15) |
Psychosis | 8 (8) |
Acute inflammatory demyelinating polyneuropathy | 0 (0) |
Autonomic disorder | 1 (1) |
Mononeuropathy | 2 (2) |
Myasthenia gravis | 0 (0) |
Neuropathy, cranial | 9 (9) |
Plexopathy | 0 (0) |
Polyneuropathy | 8 (8) |
Other than ACR1999 syndromes | 24 (24) |
Cerebral vasculitis | 10 (10) |
Organic brain syndrome/lethargy | 4 (4) |
(Pyramidal) walking disorder | 4 (5) |
Ocular problems, other | 2 (2) |
Increased cranial pressure | 1 (1) |
Paresis left arm and dysarthria | 1 (1) |
Motor disorder left arm | 1 (1) |
Apraxia | 1 (1) |
Results are presented as n (%).
ACR, American College of Rheumatology; NPSLE, neuropsychiatric SLE.