Multivariable logistic regression models for COVID-19 outcomes comparing patients with SLE vs matched controls
| Model 1* OR (95% CI) | Model 2† OR (95% CI) | Model 3‡ OR (95% CI) | Model 4§ OR (95% CI) | |
| 30-day mortality | ||||
| Control | 1 | 1 | 1 | 1 |
| SLE | 2.21 (1.40 to 3.49) | 2.09 (1.31 to 3.32) | 1.48 (0.92 to 2.38) | 1.39 (0.79 to 2.44) |
| 30-day mechanical ventilation | ||||
| Control | 1 | 1 | 1 | 1 |
| SLE | 2.54 (1.76 to 3.67) | 2.43 (1.67 to 3.54) | 1.40 (0.95 to 2.07) | 1.81 (1.16 to 2.82) |
| 30-day hospitalisation | ||||
| Control | 1 | 1 | 1 | 1 |
| SLE | 2.16 (1.79 to 2.59) | 2.06 (1.71 to 2.49) | 1.32 (1.08 to 1.61) | 1.32 (1.05 to 1.65) |
| 30-day ICU without mechanical ventilation | ||||
| Control | 1 | 1 | 1 | 1 |
| SLE | 1.95 (1.41 to 2.70) | 1.82 (1.31 to 2.53) | 1.12 (0.80 to 1.58) | 0.94 (0.62 to 1.41) |
*Model 1 included adjustments for age, gender, race and ethnicity, COVID-19 quarter diagnosis, insurance and region.
†Model 2 included adjustments from model 1 and obesity, smoking status, skilled nursing facility admission within 3 months before COVID-19 diagnosis.
‡Model 3 included adjustments from Model 2 and for number of comorbidities (0, 1 or 2+) excluding SLE.
§Model 4 included adjustments for model 2 and for individual comorbidities.
COVID-19, coronavirus disease 19; ICU, intensive care unit; SLE, systemic lupus erythematosus.