Table 4

Multivariable logistic regression models of COVID-19 outcomes in patients with SLE

Mortality
OR
(95% CI)
Mechanical ventilation
OR
(95% CI)
Hospitalisation
OR
(95% CI)
ICU excluding mechanical ventilation
OR (95% CI)
SLE Disease Activity
 Mild (reference value)1111
 Moderate1.76
(0.66 to 4.69) p=0.26
1.59
(0.68 to 3.74) p=0.29
2.01
(1.31 to 3.07) p=0.001
1.02
(0.50 to 2.08) p=0.95
 Severe2.38
(0.85 to 6.66) p=0.10
5.83
(2.60 to 13.07) p<0.001
3.97
(2.37 to 6.65) p<0.001
0.90
(0.38 to 2.12) p=0.85
  • All models were adjusted for Belimumab in 6 months before positive COVID-19. Additionally, model for 30-day mortality was additionally adjusted for age, race and insurance type. Model for 30-day mechanical ventilation was adjusted for age, COVID-19 diagnosis quarter, skilled nurse facility in 3 months before positive COVID-19 and severe obesity. Model for 30-day hospitalisation was adjusted for age, COVID-19 diagnosis quarter, smoking status, insurance type and region. Model for 30-day ICU excluding ventilation was adjusted for age, severe obesity and region. Association with Garris index levels of severity.

  • COVID-19, coronavirus disease 19; ICU, intensive care unit; SLE, systemic lupus erythematosus.