Cumulative* disease flares and hospitalisations
| Total | Male | Female | P value | |
| Patients with flares >0, n (%) | ||||
| At 5 years | 138/359 (38.4) | 15/42 (35.7) | 123/317 (38.8) | 0.7 |
| At last visit | 249/401 (62.1) | 26/49 (53) | 223/352 (63.3) | 0.16 |
| Patients with ≥1 severe flare, n (%) | 144/359 (40.1) | 17/46 (37) | 127/313 (40.6) | 0.64 |
| Number of flares, mean±SD | ||||
| At 5 years | 1.5±0.9 | 1.6±1 | 1.5±0.9 | n.s. |
| At 10 years | 1.8±1.1 | 1.8±1 | 1.8±1.1 | n.s. |
| Median (IQR 25%–75%) | ||||
| At 1 year | 1 (1–2) | 1 (1–2) | 1 (1–2) | |
| At 5 years | 1 (1–2) | 1 (1–2) | 1 (1–2) | |
| At 10 years | 1 (1–2) | 1 (1–2) | 1 (1–2) | |
| Hospitalisations† >0, n (%) | ||||
| At 1 year | 251/417 (60.2) | 33/51 (64.7) | 218/366 (59.5) | 0.48 |
| At 5 years | 309/417 (74.1) | 40/51 (78.4) | 269/366 (73.4) | 0.45 |
| At 10 years | 404/417 (96.9) | 51/51 (100) | 353/366 (96.2) | 0.15 |
| Number of hospitalisations, mean±SD | ||||
| At 1 year | 1.3±0.6 | 1.3±0.7 | 1.3±0.5 | 0.97 |
| At 5 years | 1.9±1.6 | 2.6±2.8 | 1.8±1.4 | 0.65 |
| At 10 years | 3±2.8 | 5.5±5.2 | 2.7±2.4 | 0.24 |
| Median (IQR 25%–75%) | ||||
| At 1 year | 1 (1–1) | 1 (1–1) | 1 (1–1) | |
| At 5 years | 1 (1–2) | 1 (1–3) | 1 (1–2) | |
| At 10 years | 2 (1–4) | 4 (2.5–8.5) | 2 (1–4) | |
*After disease onset.
†For any cause.