Table 1

Demographic characteristics of the whole cohort and of male and female patients

Demographic characteristicsTotalMaleFemaleP value
Number of patients, n (%)41751/417 (12.2)366/417 (87.8)
Inception cohort, n (%)260/417 (62.3)36/51 (70.6)224/366 (61.2)0.19
Age at last visit
 Mean±SD46±13.248.1±14.345.7±130.17
 Median (IQR 25%–75%)46 (36–55)48 (41–56)45 (35–51)
 Caucasian ethnicity, n (%)417/417 (100)51/51 (100)366/366 (100)
 Smokers,* n (%)124/409 (30.3)24/50 (48)100/359 (29.5)0.004
Follow-up (years)
 Mean±SD10.7±9.37.6±7.611.1±9.50.006
 Median (IQR 25%–75%)7 (3–17)4 (2–10)7 (3–18)
Disease duration (years)
 Mean±SD16.84±9.8112.8±1.317.4±0.510.001
 Median (IQR 25%–75%)16 (8–24)10 (6–19)17 (9–25)
Age at disease onset (years)
 Mean±SD29.2±11.935.3±14.128.3±11.30.0007
 Median (IQR 25%–75%)27 (20–37)34 (23–46)26 (20–35)
Age at diagnosis (years)
 Mean±SD31.4±12.638.17±14.830.47±12<0.001
 Median (IQR 25%–75%)29 (21–40)41 (23–50)28 (21–38)
 Late onset, n (%)29/417 (6.9)10/51 (19.6)19/366 (5.2)<0.0001
 Childhood onset, n (%)33/417 (7.9)1/51 (1.9)32/366 (8.7)0.09
Delay between onset and diagnosis (years)
 Mean±SD2.2±4.22.8±5.22.17±4.10.32
 Median (IQR 25%–75%)0 (0–3)0 (0–3)0 (0–3)
  • Statistically significant p-values are in bold.

  • *Ever.