Case | Age/sex | LN status | C5b-9 staining | LN class | Simultaneous skin/renal biopsy | AI/CI score | IFTA (%) | uPCR | Low C3 or C4 | Elevated dsDNA |
1 | 35F | Active | Negative | III/V | Yes | 2/2 | 10 | 2.12 | Yes | Yes |
2 | 29F | Inactive | Positive | III | No | 6/2 | 10 | 0 | No | Yes |
3* | 44F | Inactive | Negative | IV | No | 0.37 | Yes | No | ||
4 | 46M | Active | Positive | IV | Yes | 8/2 | 15 | 5.8 | Yes | Yes |
5 | 25F | Inactive | Negative | III | No | 6/6 | 10 | 0.64 | No | Yes |
6* | 28F | Inactive | Negative | V | No | 0.11 | No | No | ||
7*† | 57F | Inactive | Negative | No | ||||||
8 | 43F | Inactive | Negative | III | No | 7/2 | 5 | 0 | No | No |
9 | 22M | Active | Positive | IV/V | Yes | 6/4 | 30 | 2.9 | No | Yes |
10 | 39F | Active | Positive | IV | Yes | 12/6 | 35 | 4.6 | Yes | Yes |
11 | 58M | Inactive | Negative | IV/V | No | 14/2 | 30 | 0.7 | Yes | Yes |
12 | 34F | Inactive | Negative | V | Yes | 0/1 | 5 | 1.2 | Yes | Yes |
13 | 25F | Active | Positive | III | No | 5/6 | 25 | 6.46 | No | Yes |
14 | 30F | Active | Negative | IV/V | Yes | 13/5 | 30 | 2.76 | Yes | Yes |
15 | 51M | Active | Negative | IV | Yes | 15/5 | 40 | 2.70 | Yes | Yes |
16 | 30F | Active | Positive | III | Yes | 10/0 | 7.5 | 9.80 | Yes | Yes |
*Renal biopsy interpretation not available in electronic health record.
†Anuric and did not provide labs at visit.
AI, Activity Index; CI, Chronicity Index; dsDNA, double-stranded DNA; IFTA, interstitial fibrosis tubular atrophy; LN, lupus nephritis; uPCR, urine protein creatinine ratio.